Matches in SemOpenAlex for { <https://semopenalex.org/work/W2601396686> ?p ?o ?g. }
- W2601396686 abstract "Angiopoietin 2 (ANG2) is a proangiogenic cytokine which may have an implication in neovascular age related macular degeneration (nAMD). In 24 eyes of 24 subjects presenting with treatment naïve nAMD and 26 eyes of 26 control patients, aqueous humor samples were collected at the time of intervention (intravitreal injection of anti-vascular endothelial growth factor or cataract extraction). Best corrected visual acuity (BCVA) with and central macular thickness (CMT) using optical coherence tomography (OCT) were measured before each injection in the nAMD group. Aqueous cytokine levels were determined by immunoassay using a multiplex array (Quansys Biosciences, Logan, UT). Levels of ANG2 in the aqueous were significantly higher in nAMD patients than those of the control group (p < 0.0001), so were hepatocyte growth factor (HGF), interleukin-8 (IL-8) and tissue inhibitor of metalloproteinase 1 (TIMP 1), all with p < 0.001. ANG2 correlated with worse BCVA (r = 0.44, p-value = 0.027) and greater CMT (r = 0.66, p-value < 0.0001) on optical coherence tomography (OCT). ANG2 is upregulated in patients with nAMD and correlates with severity of disease at presentation." @default.
- W2601396686 created "2017-04-07" @default.
- W2601396686 creator A5006583510 @default.
- W2601396686 creator A5020963678 @default.
- W2601396686 creator A5029075552 @default.
- W2601396686 creator A5029106850 @default.
- W2601396686 creator A5046932702 @default.
- W2601396686 creator A5058936463 @default.
- W2601396686 creator A5063121790 @default.
- W2601396686 creator A5039305172 @default.
- W2601396686 date "2017-03-27" @default.
- W2601396686 modified "2023-10-14" @default.
- W2601396686 title "Elevated angiopoietin 2 in aqueous of patients with neovascular age related macular degeneration correlates with disease severity at presentation" @default.
- W2601396686 cites W1481978003 @default.
- W2601396686 cites W1486264823 @default.
- W2601396686 cites W1632120505 @default.
- W2601396686 cites W1971968805 @default.
- W2601396686 cites W1989274306 @default.
- W2601396686 cites W1994550232 @default.
- W2601396686 cites W1999053742 @default.
- W2601396686 cites W2001825182 @default.
- W2601396686 cites W2004117352 @default.
- W2601396686 cites W2007088268 @default.
- W2601396686 cites W2026184172 @default.
- W2601396686 cites W2034512261 @default.
- W2601396686 cites W2042345981 @default.
- W2601396686 cites W2042350316 @default.
- W2601396686 cites W2043208670 @default.
- W2601396686 cites W2049414526 @default.
- W2601396686 cites W2049624292 @default.
- W2601396686 cites W2051149451 @default.
- W2601396686 cites W2065187621 @default.
- W2601396686 cites W2077762392 @default.
- W2601396686 cites W2080591818 @default.
- W2601396686 cites W2081872783 @default.
- W2601396686 cites W2086161618 @default.
- W2601396686 cites W2102167881 @default.
- W2601396686 cites W2102195694 @default.
- W2601396686 cites W2119187102 @default.
- W2601396686 cites W2120264291 @default.
- W2601396686 cites W2124415048 @default.
- W2601396686 cites W2128817601 @default.
- W2601396686 cites W2143760058 @default.
- W2601396686 cites W2147358575 @default.
- W2601396686 cites W2163616867 @default.
- W2601396686 cites W2164122959 @default.
- W2601396686 cites W2166075836 @default.
- W2601396686 cites W2170000965 @default.
- W2601396686 cites W2192931230 @default.
- W2601396686 cites W2530682636 @default.
- W2601396686 cites W30448767 @default.
- W2601396686 cites W763617670 @default.
- W2601396686 doi "https://doi.org/10.1038/srep45081" @default.
- W2601396686 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5366858" @default.
- W2601396686 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28345626" @default.
- W2601396686 hasPublicationYear "2017" @default.
- W2601396686 type Work @default.
- W2601396686 sameAs 2601396686 @default.
- W2601396686 citedByCount "35" @default.
- W2601396686 countsByYear W26013966862017 @default.
- W2601396686 countsByYear W26013966862018 @default.
- W2601396686 countsByYear W26013966862019 @default.
- W2601396686 countsByYear W26013966862020 @default.
- W2601396686 countsByYear W26013966862021 @default.
- W2601396686 countsByYear W26013966862022 @default.
- W2601396686 countsByYear W26013966862023 @default.
- W2601396686 crossrefType "journal-article" @default.
- W2601396686 hasAuthorship W2601396686A5006583510 @default.
- W2601396686 hasAuthorship W2601396686A5020963678 @default.
- W2601396686 hasAuthorship W2601396686A5029075552 @default.
- W2601396686 hasAuthorship W2601396686A5029106850 @default.
- W2601396686 hasAuthorship W2601396686A5039305172 @default.
- W2601396686 hasAuthorship W2601396686A5046932702 @default.
- W2601396686 hasAuthorship W2601396686A5058936463 @default.
- W2601396686 hasAuthorship W2601396686A5063121790 @default.
- W2601396686 hasBestOaLocation W26013966861 @default.
- W2601396686 hasConcept C118487528 @default.
- W2601396686 hasConcept C126322002 @default.
- W2601396686 hasConcept C167734588 @default.
- W2601396686 hasConcept C170493617 @default.
- W2601396686 hasConcept C2776403814 @default.
- W2601396686 hasConcept C2776694085 @default.
- W2601396686 hasConcept C2776996007 @default.
- W2601396686 hasConcept C2777025900 @default.
- W2601396686 hasConcept C2777802072 @default.
- W2601396686 hasConcept C2778257484 @default.
- W2601396686 hasConcept C2778690821 @default.
- W2601396686 hasConcept C2778818243 @default.
- W2601396686 hasConcept C2781100027 @default.
- W2601396686 hasConcept C2993390227 @default.
- W2601396686 hasConcept C71924100 @default.
- W2601396686 hasConceptScore W2601396686C118487528 @default.
- W2601396686 hasConceptScore W2601396686C126322002 @default.
- W2601396686 hasConceptScore W2601396686C167734588 @default.
- W2601396686 hasConceptScore W2601396686C170493617 @default.
- W2601396686 hasConceptScore W2601396686C2776403814 @default.
- W2601396686 hasConceptScore W2601396686C2776694085 @default.
- W2601396686 hasConceptScore W2601396686C2776996007 @default.
- W2601396686 hasConceptScore W2601396686C2777025900 @default.
- W2601396686 hasConceptScore W2601396686C2777802072 @default.