Matches in SemOpenAlex for { <https://semopenalex.org/work/W2601523759> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2601523759 endingPage "50" @default.
- W2601523759 startingPage "45" @default.
- W2601523759 abstract "本研究采用酵母突变株K6001作为生物活性筛选系统，对韩国圃美多公司多个产品进行筛选，发现玛咖超临界提取粉末具有较好的抗衰老活性。因此对该原料中的抗衰老活性物质进行了研究并从中分离得到了两个活性化合物(1, 2)。这两个化合物都能显著延长酵母突变株的复制性寿命。通过波谱分析以及文献数据比对，推测活性化合物1的结构为n-benzyl-(9Z)-octadecenamide(1)，确定活性化合物2的结构为n-benzylmyristamide(2)。为了进一步确认化合物1的结构，合成了n-benzyl-(9Z)-octadecena- mide(1)，并且测定了其生物活性，结果表明合成得到的n-benzyl-(9Z)-octadecenamide的波谱数据及生物活性与天然来源的化合物1相同。 Extracts of several products of Pulmuone were screened for their anti-aging activity using the K6001 yeast strain bioassay system. Maca supercritical extract significantly exhibited anti-aging activity and two active compounds were isolated from the extract. The structures were elucidated by the spectroscopic data and comparison with those reported. One structure was proposed to be n-benzyl-(9Z)-octadecenamide (1), and another was identified as n-benzylmyristamide (2). Both compounds significantly extended the replicative lifespan of K6001 yeast strain. To confirm the structure of compound 1, n-benzyl-(9Z)-octadecenamide (1) was synthesized and biological activity was evaluated. The synthesized n-benzyl-(9Z)-octadecenamide (1) is identical to natural compound 1 from spectroscopic data and biological activity." @default.
- W2601523759 created "2017-04-07" @default.
- W2601523759 creator A5030157497 @default.
- W2601523759 date "2017-01-01" @default.
- W2601523759 modified "2023-10-17" @default.
- W2601523759 title "Anti-Aging Substances from Maca Supercritical Extract" @default.
- W2601523759 cites W1939577241 @default.
- W2601523759 cites W1969891492 @default.
- W2601523759 cites W2011344652 @default.
- W2601523759 cites W2015411731 @default.
- W2601523759 cites W2044261849 @default.
- W2601523759 cites W2046821330 @default.
- W2601523759 cites W2063939130 @default.
- W2601523759 cites W2076996341 @default.
- W2601523759 cites W2084803824 @default.
- W2601523759 cites W2087019732 @default.
- W2601523759 cites W2136078821 @default.
- W2601523759 cites W2152659813 @default.
- W2601523759 cites W2460124445 @default.
- W2601523759 cites W2466333719 @default.
- W2601523759 doi "https://doi.org/10.12677/jocr.2017.51007" @default.
- W2601523759 hasPublicationYear "2017" @default.
- W2601523759 type Work @default.
- W2601523759 sameAs 2601523759 @default.
- W2601523759 citedByCount "0" @default.
- W2601523759 crossrefType "journal-article" @default.
- W2601523759 hasAuthorship W2601523759A5030157497 @default.
- W2601523759 hasBestOaLocation W26015237591 @default.
- W2601523759 hasConcept C118419359 @default.
- W2601523759 hasConcept C178790620 @default.
- W2601523759 hasConcept C185592680 @default.
- W2601523759 hasConcept C556039675 @default.
- W2601523759 hasConcept C71924100 @default.
- W2601523759 hasConceptScore W2601523759C118419359 @default.
- W2601523759 hasConceptScore W2601523759C178790620 @default.
- W2601523759 hasConceptScore W2601523759C185592680 @default.
- W2601523759 hasConceptScore W2601523759C556039675 @default.
- W2601523759 hasConceptScore W2601523759C71924100 @default.
- W2601523759 hasIssue "01" @default.
- W2601523759 hasLocation W26015237591 @default.
- W2601523759 hasOpenAccess W2601523759 @default.
- W2601523759 hasPrimaryLocation W26015237591 @default.
- W2601523759 hasRelatedWork W1531601525 @default.
- W2601523759 hasRelatedWork W1990781990 @default.
- W2601523759 hasRelatedWork W2117371498 @default.
- W2601523759 hasRelatedWork W2314643286 @default.
- W2601523759 hasRelatedWork W2607424097 @default.
- W2601523759 hasRelatedWork W2748952813 @default.
- W2601523759 hasRelatedWork W2899084033 @default.
- W2601523759 hasRelatedWork W2948807893 @default.
- W2601523759 hasRelatedWork W2949555104 @default.
- W2601523759 hasRelatedWork W2778153218 @default.
- W2601523759 hasVolume "05" @default.
- W2601523759 isParatext "false" @default.
- W2601523759 isRetracted "false" @default.
- W2601523759 magId "2601523759" @default.
- W2601523759 workType "article" @default.