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- W2601722932 abstract "Introduction: Leadless pacemakers are designed to eliminate lead and pocket based complications that occur with transvenous systems. The Micra Transcatheter Pacing Study demonstrated a 99.2% implant success rate and achieved its primary safety and efficacy objectives when 300 patients were followed for 6 months. We compared major complication rates with a larger cohort of Micra patients followed beyond 6 months to patients with transvenous systems. Methods: Micra patients (N = 726) with an implant attempt were included in this analysis. A pre-defined historical control group of 2667 transvenous pacemaker patients from 6 studies conducted from 2000 to 2012 was used for comparison. A Cox model compared device and procedure related major complications between device types. Sub-group analysis by age, sex, and co-morbidity was performed to test for interaction effect. Results: The Micra patients were older (76 ± 11 yrs vs 71 ± 12 yrs, P < 0.001) and had more comorbidities than transvenous patients. Through the average follow-up duration of 7.7 ± 3.9 months (range 0 - 19.1), Micra patients experienced significantly fewer major complications compared to transvenous patients (hazard ratio: 0.48; 95% confidence interval: 0.32-0.72; P < 0.001), driven by the absence of lead-related complications with Micra. Across all patient subgroups, there was no significant interaction and Micra provided a consistently lower risk of major complication through 7.7-months compared to traditional transvenous systems." @default.
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- W2601722932 date "2016-06-01" @default.
- W2601722932 modified "2023-10-17" @default.
- W2601722932 title "102-02: Looking Beyond Six Months: Results From the Micra Transcatheter Pacing Study" @default.
- W2601722932 doi "https://doi.org/10.1093/europace/18.suppl_1.i83a" @default.
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