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- W2602005220 endingPage "2039" @default.
- W2602005220 startingPage "2031" @default.
- W2602005220 abstract "Migraine is a common brain disorder with high disability rates which involves a series of abnormal neuronal networks, interacting at different levels of the central and peripheral nervous system. An increase in the interest around migraine pathophysiology has allowed researchers to unravel certain neurophysiological mechanisms and neurotransmitter involvement culminating in the recent development of novel therapies, which might substantially change the clinical approach to migraine patients. The present review will highlight the current aspects of migraine pathophysiology, covering an understanding of the complex workings of the migraine state and the brain regions responsible for them. We will further discuss the therapeutic agents which have appeared in the most recent years for migraine care, from calcitonin gene-related peptide (CGRP) receptor antagonists, gepants; through serotonin 5-HT1F receptor agonists, ditans, and CGRP or CGRP receptor monoclonal antibodies to invasive and non-invasive neuromodulation techniques." @default.
- W2602005220 created "2017-04-07" @default.
- W2602005220 creator A5005334403 @default.
- W2602005220 creator A5013044201 @default.
- W2602005220 creator A5058994427 @default.
- W2602005220 date "2017-03-20" @default.
- W2602005220 modified "2023-10-14" @default.
- W2602005220 title "An update on migraine: current understanding and future directions" @default.
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