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- W2602439077 abstract "Follicular thyroid carcinoma (FTC) metastasis to the facial skeleton is exceedingly rare. A case of FTC metastasizing to the mandible is presented and a systematic review of the literature describing thyroid metastasis to the facial skeleton is performed. A 73-year-old female presented with metastatic FTC to the mandible and underwent total thyroidectomy, segmental mandibulectomy, bone impacted fibular free flap reconstruction, and adjuvant radioactive iodine treatment. The PubMed database was searched for literature describing thyroid cancer with facial skeleton metastasis using the key words “thyroid,” “cancer,” “carcinoma,” “metastasis,” and “malignancy” with “oral cavity,” “maxilla,” “mandible,” “sinus,” “paranasal,” and “orbit.” Reports that only involved the soft tissues were excluded. Systematic review revealed 59 cases of well-differentiated thyroid cancer with facial skeleton metastasis: 35 mandibular metastases (21 = FTC), 6 maxilla metastases (2 = FTC), 9 orbital metastases (4 = FTC), and 11 paranasal sinus metastases (7 = FTC). Treatment included surgery, RAI, external beam radiotherapy (XRT), or a combination of these modalities. The one, two, and five-year survival rates were 100%, 79%, and 16%, respectively. Facial skeleton metastasis of FTC is a rare clinical challenge. Optimal treatment appears to include total thyroidectomy and resection of involved structures with or without adjuvant treatment." @default.
- W2602439077 created "2017-04-07" @default.
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- W2602439077 date "2017-03-28" @default.
- W2602439077 modified "2023-09-25" @default.
- W2602439077 title "Follicular thyroid carcinoma metastasis to the facial skeleton: a systematic review" @default.
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- W2602439077 doi "https://doi.org/10.1186/s12885-017-3199-3" @default.
- W2602439077 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5370488" @default.
- W2602439077 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28351395" @default.
- W2602439077 hasPublicationYear "2017" @default.
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