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- W2602481502 abstract "Findings have shown that low serum 25-hydroxy vitamin D level is a possible risk factor for incidence of preeclampsia during pregnancy. Vitamin D has important effects on multiple biological pathways, including angiogenesis. Some studies have shown that vitamin D deficiency is highly prevalent among women suffering from preeclampsia, influencing immune modulation and vascular function. Evidence has shown that an imbalance of pro-antigenic and anti-angiogenic proteins can be considered as a possible etiological factor in the development of preeclampsia. Besides, there is a series of studies linking the renin–angiotensin aldosterone system (RAAS) with preeclampsia. In this article, we review the current studies evaluating the association between maternal vitamin D status and vascular health, metabolism, placental immune function and the risk of preeclampsia. We provided evidence of the different factor involved in the metabolism of vitamin D and vitamin D receptor (VDR) expression, gene regulations, immune function, and chronic disease when vitamin D is used optimally." @default.
- W2602481502 created "2017-04-07" @default.
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- W2602481502 date "2017-01-01" @default.
- W2602481502 modified "2023-09-28" @default.
- W2602481502 title "Risks associated with preeclampsia: possible mechanisms" @default.
- W2602481502 doi "https://doi.org/10.22038/rcm.2017.13735.1156" @default.
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