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- W2602599355 abstract "To assess 1-year efficacy and safety data from pilot trials ofthe Rezum System water vapor to treat lower urinary tractsymptoms (LUTS) secondary to benign prostatic hyperplasia(BPH). A total of 65 men with symptoms of moderate to severeBPH were enrolled in pilot studies at centers in the DominicanRepublic, the Czech Republic, and Sweden. Each patient wastreated with transurethral delivery of sterile water vapor(steam). International Prostate Symptom Score (1PSS), peakurinary flow (Qmax), quality of life (QoL), postvoid residual,International Index of Erectile Function, and prostate-specificantigen were evaluated at 1 week and 1, 3, 6, and 12 monthspost-treatment. Safety was also assessed. Statisticallysignificant clinical improvements at 1,3, 6, and 12 months werereported for IPSS (decreased by 6.8, 13.4, 13.1, and 12.5points, respectively) and Qmax (increased by 2.0, 4.7, 4-3, and4-6 mL/sec, respectively). At 12 months, these results equatedto a 56% improvement in IPSS (P <.001) and an 87% improvementin Qmax (P <.001). QoL also improved at 12 months with a 61%improvement. Sexual function was maintained. Most of theadverse events (AEs) were related to endoscopic instrumentationand were of short duration. One case of urinary retention wasclassified as a procedure/device-related serious AE." @default.
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- W2602599355 date "2015-01-01" @default.
- W2602599355 modified "2023-09-28" @default.
- W2602599355 title "Efficacy and Safety of Rezum System Water Vapor Treatment forLower Urinary Tract Symptoms Secondary to Benign ProstaticHyperplasia" @default.
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