Matches in SemOpenAlex for { <https://semopenalex.org/work/W2602672783> ?p ?o ?g. }
- W2602672783 endingPage "2530" @default.
- W2602672783 startingPage "2517" @default.
- W2602672783 abstract "Negatively charged silver nanoparticles with potent antibacterial activity and reduced toxicity for pharmaceutical preparations Lucia Salvioni,1 Elisabetta Galbiati,1 Veronica Collico,1 Giulia Alessio,1 Svetlana Avvakumova,1 Fabio Corsi,2,3 Paolo Tortora,1 Davide Prosperi,1 Miriam Colombo1 1Nanobiolab, Department of Biotechnology and Bioscience, University of Milano-Bicocca, 2Biological and Clinical Science Department, University of Milan, Milano, 3Surgery Department, Breast Unit, IRCCS S Maugeri Foundation, Pavia, Italy Background: The discovery of new solutions with antibacterial activity as efficient and safe alternatives to common preservatives (such as parabens) and to combat emerging infections and drug-resistant bacterial pathogens is highly expected in cosmetics and pharmaceutics. Colloidal silver nanoparticles (NPs) are attracting interest as novel effective antimicrobial agents for the prevention of several infectious diseases.Methods: Water-soluble, negatively charged silver nanoparticles (AgNPs) were synthesized by reduction with citric and tannic acid and characterized by transmission electron microscopy, dynamic light scattering, zeta potential, differential centrifuge sedimentation, and ultraviolet–visible spectroscopy. AgNPs were tested with model Gram-negative and Gram-positive bacteria in comparison to two different kinds of commercially available AgNPs.Results: In this work, AgNPs with higher antibacterial activity compared to the commercially available colloidal silver solutions were prepared and investigated. Bacteria were plated and the antibacterial activity was tested at the same concentration of silver ions in all samples. The AgNPs did not show any significant reduction in the antibacterial activity for an acceptable time period. In addition, AgNPs were transferred to organic phase and retained their antibacterial efficacy in both aqueous and nonaqueous media and exhibited no toxicity in eukaryotic cells.Conclusion: We developed AgNPs with a 20 nm diameter and negative zeta potential with powerful antibacterial activity and low toxicity compared to currently available colloidal silver, suitable for cosmetic preservatives and pharmaceutical preparations administrable to humans and/or animals as needed. Keywords: silver nanoparticles, antibacterial activity, long-term effect, nanoparticle toxicity, phase transfer" @default.
- W2602672783 created "2017-04-07" @default.
- W2602672783 creator A5011206324 @default.
- W2602672783 creator A5019260802 @default.
- W2602672783 creator A5022446458 @default.
- W2602672783 creator A5025358618 @default.
- W2602672783 creator A5027471159 @default.
- W2602672783 creator A5028842822 @default.
- W2602672783 creator A5046028029 @default.
- W2602672783 creator A5084212220 @default.
- W2602672783 creator A5089805137 @default.
- W2602672783 date "2017-03-01" @default.
- W2602672783 modified "2023-10-11" @default.
- W2602672783 title "Negatively charged silver nanoparticles with potent antibacterial activity and reduced toxicity for pharmaceutical preparations" @default.
- W2602672783 cites W1559815414 @default.
- W2602672783 cites W1949715899 @default.
- W2602672783 cites W1977552803 @default.
- W2602672783 cites W1979973356 @default.
- W2602672783 cites W1994480476 @default.
- W2602672783 cites W1998651898 @default.
- W2602672783 cites W1999057925 @default.
- W2602672783 cites W2008978315 @default.
- W2602672783 cites W2009791213 @default.
- W2602672783 cites W2028797616 @default.
- W2602672783 cites W2030847176 @default.
- W2602672783 cites W2044734773 @default.
- W2602672783 cites W2057401975 @default.
- W2602672783 cites W2057466373 @default.
- W2602672783 cites W2059649645 @default.
- W2602672783 cites W2061073363 @default.
- W2602672783 cites W2074285442 @default.
- W2602672783 cites W2092643722 @default.
- W2602672783 cites W2104154679 @default.
- W2602672783 cites W2110773617 @default.
- W2602672783 cites W2130490785 @default.
- W2602672783 cites W2146401071 @default.
- W2602672783 cites W2146482929 @default.
- W2602672783 cites W2158558808 @default.
- W2602672783 cites W2167077438 @default.
- W2602672783 cites W2338255824 @default.
- W2602672783 cites W2793938485 @default.
- W2602672783 doi "https://doi.org/10.2147/ijn.s127799" @default.
- W2602672783 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5383075" @default.
- W2602672783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28408822" @default.
- W2602672783 hasPublicationYear "2017" @default.
- W2602672783 type Work @default.
- W2602672783 sameAs 2602672783 @default.
- W2602672783 citedByCount "95" @default.
- W2602672783 countsByYear W26026727832017 @default.
- W2602672783 countsByYear W26026727832018 @default.
- W2602672783 countsByYear W26026727832019 @default.
- W2602672783 countsByYear W26026727832020 @default.
- W2602672783 countsByYear W26026727832021 @default.
- W2602672783 countsByYear W26026727832022 @default.
- W2602672783 countsByYear W26026727832023 @default.
- W2602672783 crossrefType "journal-article" @default.
- W2602672783 hasAuthorship W2602672783A5011206324 @default.
- W2602672783 hasAuthorship W2602672783A5019260802 @default.
- W2602672783 hasAuthorship W2602672783A5022446458 @default.
- W2602672783 hasAuthorship W2602672783A5025358618 @default.
- W2602672783 hasAuthorship W2602672783A5027471159 @default.
- W2602672783 hasAuthorship W2602672783A5028842822 @default.
- W2602672783 hasAuthorship W2602672783A5046028029 @default.
- W2602672783 hasAuthorship W2602672783A5084212220 @default.
- W2602672783 hasAuthorship W2602672783A5089805137 @default.
- W2602672783 hasBestOaLocation W26026727831 @default.
- W2602672783 hasConcept C138651985 @default.
- W2602672783 hasConcept C13965031 @default.
- W2602672783 hasConcept C14631669 @default.
- W2602672783 hasConcept C155672457 @default.
- W2602672783 hasConcept C171250308 @default.
- W2602672783 hasConcept C178790620 @default.
- W2602672783 hasConcept C185592680 @default.
- W2602672783 hasConcept C192562407 @default.
- W2602672783 hasConcept C2780104969 @default.
- W2602672783 hasConcept C2781393965 @default.
- W2602672783 hasConcept C31499863 @default.
- W2602672783 hasConcept C4937899 @default.
- W2602672783 hasConcept C523546767 @default.
- W2602672783 hasConcept C54355233 @default.
- W2602672783 hasConcept C71924100 @default.
- W2602672783 hasConcept C86181022 @default.
- W2602672783 hasConcept C86803240 @default.
- W2602672783 hasConcept C98274493 @default.
- W2602672783 hasConceptScore W2602672783C138651985 @default.
- W2602672783 hasConceptScore W2602672783C13965031 @default.
- W2602672783 hasConceptScore W2602672783C14631669 @default.
- W2602672783 hasConceptScore W2602672783C155672457 @default.
- W2602672783 hasConceptScore W2602672783C171250308 @default.
- W2602672783 hasConceptScore W2602672783C178790620 @default.
- W2602672783 hasConceptScore W2602672783C185592680 @default.
- W2602672783 hasConceptScore W2602672783C192562407 @default.
- W2602672783 hasConceptScore W2602672783C2780104969 @default.
- W2602672783 hasConceptScore W2602672783C2781393965 @default.
- W2602672783 hasConceptScore W2602672783C31499863 @default.
- W2602672783 hasConceptScore W2602672783C4937899 @default.
- W2602672783 hasConceptScore W2602672783C523546767 @default.
- W2602672783 hasConceptScore W2602672783C54355233 @default.