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- W2602938963 abstract "Background: Extended cervical mediastinoscopy (ECM) is a method used for staging non-small cell lung cancer (NSCLC). Methods: Between 1998 and 2011, 159 patients underwent ECM who had left NSCLC, were retrospectively analyzed. If the cN2 was limited to the paratracheal or subcarinal spaces without infiltrating the paraortic or subaortic spaces, these cases excluded from the study (negative cases of ECM and positive cases of SCM). Patients who had been reported as cN0 by mediastinoscopy underwent thoracotomy for tumor resection. Results: Localization of the tumor was upper lobe in 81 patients (50.9%), central in 56 patients (35.3%), lower lobe in 22 patients (13.8%). ECM was successful at harvesting one or more aortopulmonary (APW) lymph nodes in 153 patients (96.2%) (#5 and #6 sampling in 82 patients, #5 or #6 sampling in 71 patients). Mediastinal lymph node metastasis was observed in 36 patients (22.6%) via mediastinoscopy. APW lymph node metastases were shown in 26 of these patients (true-positive of ECM), remaining 10 patients who had mediastinal lymph nodes metastasis that could be accessed only via SCM were exclueded. 123 patients who identified as cN0 by mediastinoscopy were operated; 64 lobectomies, 43 pneumonectomies, 16 exploratory thoracotomies. The pathological examination of the mediastinal lymphadenectomies revealed APW lymph node metastases in 11 patients (false-negative of ECM). Sensitivity, NPV and accuracy of ECM were calculated as 0.70, 0.91, and 0.92, respectively. Conclusions: ECM has an adequate NPV and accuracy in determining metastases to the APW lymph nodes in patients with left NSCLC" @default.
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- W2602938963 date "2011-09-01" @default.
- W2602938963 modified "2023-10-17" @default.
- W2602938963 title "Late-breaking abstract: The impact of extended cervical mediastinoscopy in staging of left lung carcinoma" @default.
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