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- W2602952007 abstract "Left ventricular filling pressure (LVFP) is a marker for diastolic dysfunction and heart failure (HF) with preserved ejection fraction (pEF). The interaction between arterial stiffness (AS) and elevated LVFP has not been sufficiently investigated. In 257 patients with preserved left ventricular ejection fraction (mean age: 66 years, 53% female, mean left ventricular ejection fraction: 61%) and at least one cardiovascular risk factor (eg, hypertension and diabetes) for the development of HF or a previous diagnosis of HF, LVFP was estimated in accordance with the recommendations of the American Society of Echocardiography (elevated when E/e' ≥ 13, left atrial volume index ≥ 34 mL/m2). LVFP was correlated with radial pulse wave analysis (augmentation index normalized by 75 b/min [AIx@75]) and carotid-femoral pulse wave velocity (cfPWV). Thirty-eight percent of patients demonstrated an elevated LVFP. These patients were significantly older (68.3 ± 7.4 vs. 63.5 ± 7.6 years, P < .001), demonstrated a higher body mass index (29.8 ± 4.6 vs. 28.0 ± 5.0; P < .01), presented more often with hypertension (89.7% vs. 73.1%, P < .01), hypercholesterolemia (32.0% vs. 21.3%, P < .05), dyspnea on exertion (28.4% vs. 16.6%, P < .05), and peripheral edema (25.3% vs. 10.2%, P < .01). cfPWV and AIx@75 and were significantly elevated in patients with elevated LVFP (12.2 ± 2.7 m/s vs. 10.5 ± 2.6 m/s, P < .001, an 29.2 ± 6.7% vs. 27.4 ± 6.7%, P < .05 respectively). cfPWV and AIx@75 were correlated with echocardiographic parameters, that is, posterior wall thickness (r = 0.292, P < .001; r = 0.167, P < .01), left ventricular mass index (r = 0.255, P < .001; r = -0.192, P < .01), e' (r = -0.508, P < .001; r = -0.159, P < .05), and E/e' (r = 0.380, P < .001; r = 0.200, P < .01). cfPWV correlated with left atrial volume index (r = 0.189, P < .05) and increasing E/A ratio (r = -0.334, P < .001). Multivariate linear regression analysis demonstrated age and PWV as most important and independent predictors of LVFP elevation in the cohort. Increased AS measured by cfPWV was associated with an elevated LVFP in patients with preserved systolic function. Whether targeting AS as a major component of diastolic dysfunction and HF with preserved ejection fraction needs to be further investigated." @default.
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- W2602952007 date "2017-05-01" @default.
- W2602952007 modified "2023-10-16" @default.
- W2602952007 title "Arterial stiffness and elevated left ventricular filling pressure in patients at risk for the development or a previous diagnosis of HF—A subgroup analysis from the DIAST-CHF study" @default.
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- W2602952007 cites W1693841936 @default.
- W2602952007 cites W1971090864 @default.
- W2602952007 cites W1974691053 @default.
- W2602952007 cites W1985765388 @default.
- W2602952007 cites W1989044988 @default.
- W2602952007 cites W1990155999 @default.
- W2602952007 cites W2008943293 @default.
- W2602952007 cites W2011130900 @default.
- W2602952007 cites W2012122407 @default.
- W2602952007 cites W2029740267 @default.
- W2602952007 cites W2029921616 @default.
- W2602952007 cites W2037092081 @default.
- W2602952007 cites W2037820727 @default.
- W2602952007 cites W2042293234 @default.
- W2602952007 cites W2042545113 @default.
- W2602952007 cites W2044076817 @default.
- W2602952007 cites W2045213627 @default.
- W2602952007 cites W2049186810 @default.
- W2602952007 cites W2059624731 @default.
- W2602952007 cites W2063543521 @default.
- W2602952007 cites W2070742041 @default.
- W2602952007 cites W2072141581 @default.
- W2602952007 cites W2072941257 @default.
- W2602952007 cites W2076674903 @default.
- W2602952007 cites W2081284931 @default.
- W2602952007 cites W2083361664 @default.
- W2602952007 cites W2089923812 @default.
- W2602952007 cites W2093817104 @default.
- W2602952007 cites W2094710372 @default.
- W2602952007 cites W2096866238 @default.
- W2602952007 cites W2097189176 @default.
- W2602952007 cites W2101099004 @default.
- W2602952007 cites W2101791328 @default.
- W2602952007 cites W2102080772 @default.
- W2602952007 cites W2106650625 @default.
- W2602952007 cites W2108211140 @default.
- W2602952007 cites W2108419602 @default.
- W2602952007 cites W2110552101 @default.
- W2602952007 cites W2127039247 @default.
- W2602952007 cites W2127254785 @default.
- W2602952007 cites W2128015742 @default.
- W2602952007 cites W2134463370 @default.
- W2602952007 cites W2141402104 @default.
- W2602952007 cites W2141731247 @default.
- W2602952007 cites W2142211580 @default.
- W2602952007 cites W2147355061 @default.
- W2602952007 cites W2147483495 @default.
- W2602952007 cites W2157824930 @default.
- W2602952007 cites W2161315307 @default.
- W2602952007 cites W2161841978 @default.
- W2602952007 cites W2166004141 @default.
- W2602952007 cites W2168072390 @default.
- W2602952007 cites W2169354842 @default.
- W2602952007 cites W2199026587 @default.
- W2602952007 cites W2323862874 @default.
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- W2602952007 cites W3022179669 @default.
- W2602952007 cites W3207049299 @default.
- W2602952007 cites W38725997 @default.
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- W2602952007 doi "https://doi.org/10.1016/j.jash.2017.03.006" @default.
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