Matches in SemOpenAlex for { <https://semopenalex.org/work/W2603486571> ?p ?o ?g. }
- W2603486571 endingPage "768" @default.
- W2603486571 startingPage "757" @default.
- W2603486571 abstract "A systematic conformational search was carried out for monomers and homohexamers of furanoid β-amino acids: cis-(S,R) and trans-(S,S) stereoisomers of aminocyclopentane carboxylic acid (ACPC), two different aminofuranuronic acids (AFUα and AFUβ), their isopropylidene derivatives (AFU(ip)), and the key intermediate β-aminotetrahydrofurancarboxylic acid (ATFC). The stereochemistry of the building blocks was chosen to match that of the natural sugar amino acid (xylose and ribose) precursors (XylAFU and RibAFU). The results show that hexamers of cis-furanoid β-amino acids show great variability: while hydrophobic cyclopentane (cis-ACPC)6 and hydrophilic (XylAFUα/β)6 foldamers favor two different zigzagged conformation as hexamers, the backbone fold turns into a helix in the case of (cis-ATFC)6 (10-helix) and (XylAFU(ip))6 (14-helix). Trans stereochemistry resulted in hexamers exclusively with the right-handed helix conformation, (H12P)6, regardless of their polarity. We found that the preferred oligomeric structure of XylAFUα/β is conformationally compatible with β-pleated sheets, while that of the trans/(S,S) units matches with α-helices of proteins." @default.
- W2603486571 created "2017-04-07" @default.
- W2603486571 creator A5006131966 @default.
- W2603486571 creator A5027972607 @default.
- W2603486571 creator A5062909663 @default.
- W2603486571 creator A5065713814 @default.
- W2603486571 creator A5087296863 @default.
- W2603486571 date "2017-04-11" @default.
- W2603486571 modified "2023-10-18" @default.
- W2603486571 title "Predictable Conformational Diversity in Foldamers of Sugar Amino Acids" @default.
- W2603486571 cites W1969141061 @default.
- W2603486571 cites W1969877547 @default.
- W2603486571 cites W1984599229 @default.
- W2603486571 cites W1986326797 @default.
- W2603486571 cites W1990871455 @default.
- W2603486571 cites W2001392646 @default.
- W2603486571 cites W2009435459 @default.
- W2603486571 cites W2018717750 @default.
- W2603486571 cites W2029212992 @default.
- W2603486571 cites W2032891742 @default.
- W2603486571 cites W2037780945 @default.
- W2603486571 cites W2040408807 @default.
- W2603486571 cites W2044865569 @default.
- W2603486571 cites W2045878175 @default.
- W2603486571 cites W2050486326 @default.
- W2603486571 cites W2057597527 @default.
- W2603486571 cites W2061545824 @default.
- W2603486571 cites W2065526492 @default.
- W2603486571 cites W2071783339 @default.
- W2603486571 cites W2074986801 @default.
- W2603486571 cites W2092519531 @default.
- W2603486571 cites W2094395502 @default.
- W2603486571 cites W2121919924 @default.
- W2603486571 cites W2125621895 @default.
- W2603486571 cites W2132718917 @default.
- W2603486571 cites W2228084574 @default.
- W2603486571 cites W2335029105 @default.
- W2603486571 cites W2464060564 @default.
- W2603486571 cites W2498505638 @default.
- W2603486571 cites W2547250258 @default.
- W2603486571 cites W2549029237 @default.
- W2603486571 cites W4235088937 @default.
- W2603486571 doi "https://doi.org/10.1021/acs.jcim.6b00488" @default.
- W2603486571 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28345931" @default.
- W2603486571 hasPublicationYear "2017" @default.
- W2603486571 type Work @default.
- W2603486571 sameAs 2603486571 @default.
- W2603486571 citedByCount "4" @default.
- W2603486571 countsByYear W26034865712018 @default.
- W2603486571 countsByYear W26034865712019 @default.
- W2603486571 countsByYear W26034865712023 @default.
- W2603486571 crossrefType "journal-article" @default.
- W2603486571 hasAuthorship W2603486571A5006131966 @default.
- W2603486571 hasAuthorship W2603486571A5027972607 @default.
- W2603486571 hasAuthorship W2603486571A5062909663 @default.
- W2603486571 hasAuthorship W2603486571A5065713814 @default.
- W2603486571 hasAuthorship W2603486571A5087296863 @default.
- W2603486571 hasBestOaLocation W26034865712 @default.
- W2603486571 hasConcept C166940927 @default.
- W2603486571 hasConcept C178790620 @default.
- W2603486571 hasConcept C185592680 @default.
- W2603486571 hasConcept C18903297 @default.
- W2603486571 hasConcept C2778530040 @default.
- W2603486571 hasConcept C2778556512 @default.
- W2603486571 hasConcept C2779965526 @default.
- W2603486571 hasConcept C515207424 @default.
- W2603486571 hasConcept C521977710 @default.
- W2603486571 hasConcept C55493867 @default.
- W2603486571 hasConcept C71240020 @default.
- W2603486571 hasConcept C86803240 @default.
- W2603486571 hasConceptScore W2603486571C166940927 @default.
- W2603486571 hasConceptScore W2603486571C178790620 @default.
- W2603486571 hasConceptScore W2603486571C185592680 @default.
- W2603486571 hasConceptScore W2603486571C18903297 @default.
- W2603486571 hasConceptScore W2603486571C2778530040 @default.
- W2603486571 hasConceptScore W2603486571C2778556512 @default.
- W2603486571 hasConceptScore W2603486571C2779965526 @default.
- W2603486571 hasConceptScore W2603486571C515207424 @default.
- W2603486571 hasConceptScore W2603486571C521977710 @default.
- W2603486571 hasConceptScore W2603486571C55493867 @default.
- W2603486571 hasConceptScore W2603486571C71240020 @default.
- W2603486571 hasConceptScore W2603486571C86803240 @default.
- W2603486571 hasFunder F4320321994 @default.
- W2603486571 hasIssue "4" @default.
- W2603486571 hasLocation W26034865711 @default.
- W2603486571 hasLocation W26034865712 @default.
- W2603486571 hasLocation W26034865713 @default.
- W2603486571 hasOpenAccess W2603486571 @default.
- W2603486571 hasPrimaryLocation W26034865711 @default.
- W2603486571 hasRelatedWork W1803119193 @default.
- W2603486571 hasRelatedWork W1981194120 @default.
- W2603486571 hasRelatedWork W2050620361 @default.
- W2603486571 hasRelatedWork W2314776116 @default.
- W2603486571 hasRelatedWork W2405003992 @default.
- W2603486571 hasRelatedWork W2603486571 @default.
- W2603486571 hasRelatedWork W2951314966 @default.
- W2603486571 hasRelatedWork W2952200908 @default.
- W2603486571 hasRelatedWork W2952850020 @default.