FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2603538695> ?p ?o ?g. }

• W2603538695 abstract "Abstract Corticobasal degeneration is a scarce neurodegenerative disease, which can only be confirmed by histopathological examination. Reported to be associated with various clinical syndromes, its classical clinical phenotype is corticobasal syndrome. Due to the rareness of corticobasal syndrome/corticobasal degeneration and low numbers of patients included in single studies, meta-analyses are particularly suited to disentangle features of the clinical syndrome and histopathology. Using PubMed, we identified 11 magnetic resonance imaging studies measuring atrophy in 22 independent cohorts with 200 patients contrasted to 318 healthy controls. The anatomic likelihood estimation method was applied to reveal affected brain regions across studies. Corticobasal syndrome was related to gray matter loss in the basal ganglia/thalamus, frontal, parietal, and temporal lobes. In corticobasal degeneration patients, atrophy in the thalamus, frontal, temporal, and occipital lobes were found. Finally, in a conjunction analysis, the bilateral thalamus, the bilateral posterior frontomedian cortex, posterior midcingulate cortex and premotor area/supplementary motor area, and the left posterior superior and middle frontal gyrus/precentral gyrus were identified as areas associated with both, corticobasal syndrome and corticobasal degeneration. Remarkably, atrophy in the premotor area/supplementary motor area and posterior midcingulate/frontomedian cortex seems to be specific for corticobasal syndrome/corticobasal degeneration, whereas atrophy in the thalamus and the left posterior superior and middle frontal gyrus/precentral gyrus are also associated with other neurodegenerative diseases according to anatomic likelihood estimation method meta-analyses. Our study creates a new conceptual framework to understand, and distinguish between clinical features (corticobasal syndrome) and histopathological findings (corticobasal degeneration) by powerful data-driven meta-analytic approaches. Furthermore, it proposes regional-specific atrophy as an imaging biomarker for diagnosis of corticobasal syndrome/corticobasal degeneration ante-mortem." @default.
• W2603538695 created "2017-04-07" @default.
• W2603538695 creator A5005496799 @default.
• W2603538695 creator A5014560783 @default.
• W2603538695 creator A5017632965 @default.
• W2603538695 creator A5045258788 @default.
• W2603538695 creator A5058371822 @default.
• W2603538695 date "2017-03-31" @default.
• W2603538695 modified "2023-10-14" @default.
• W2603538695 title "Disentangling the neural correlates of corticobasal syndrome and corticobasal degeneration with systematic and quantitative ALE meta-analyses" @default.
• W2603538695 cites W1606558769 @default.
• W2603538695 cites W1968316463 @default.
• W2603538695 cites W1970553092 @default.
• W2603538695 cites W1984544413 @default.
• W2603538695 cites W1990792527 @default.
• W2603538695 cites W1992416557 @default.
• W2603538695 cites W2022109116 @default.
• W2603538695 cites W2036410968 @default.
• W2603538695 cites W2041615438 @default.
• W2603538695 cites W2043187980 @default.
• W2603538695 cites W2051128659 @default.
• W2603538695 cites W2060259639 @default.
• W2603538695 cites W2067395123 @default.
• W2603538695 cites W2068483718 @default.
• W2603538695 cites W2071751509 @default.
• W2603538695 cites W2072170505 @default.
• W2603538695 cites W2074815756 @default.
• W2603538695 cites W2079073956 @default.
• W2603538695 cites W2096230777 @default.
• W2603538695 cites W2098406191 @default.
• W2603538695 cites W2101548462 @default.
• W2603538695 cites W2120740638 @default.
• W2603538695 cites W2128058309 @default.
• W2603538695 cites W2134610285 @default.
• W2603538695 cites W2140255740 @default.
• W2603538695 cites W2144048828 @default.
• W2603538695 cites W2144707045 @default.
• W2603538695 cites W2146281101 @default.
• W2603538695 cites W2154285343 @default.
• W2603538695 cites W2156098321 @default.
• W2603538695 cites W2163274894 @default.
• W2603538695 cites W2164025570 @default.
• W2603538695 cites W2165130903 @default.
• W2603538695 cites W2166003124 @default.
• W2603538695 cites W2167840686 @default.
• W2603538695 cites W2283930528 @default.
• W2603538695 cites W2468996569 @default.
• W2603538695 cites W2516407199 @default.
• W2603538695 cites W4250439502 @default.
• W2603538695 cites W69591616 @default.
• W2603538695 doi "https://doi.org/10.1038/s41531-017-0012-6" @default.
• W2603538695 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5459811" @default.
• W2603538695 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28649612" @default.
• W2603538695 hasPublicationYear "2017" @default.
• W2603538695 type Work @default.
• W2603538695 sameAs 2603538695 @default.
• W2603538695 citedByCount "27" @default.
• W2603538695 countsByYear W26035386952017 @default.
• W2603538695 countsByYear W26035386952018 @default.
• W2603538695 countsByYear W26035386952019 @default.
• W2603538695 countsByYear W26035386952020 @default.
• W2603538695 countsByYear W26035386952021 @default.
• W2603538695 countsByYear W26035386952022 @default.
• W2603538695 countsByYear W26035386952023 @default.
• W2603538695 crossrefType "journal-article" @default.
• W2603538695 hasAuthorship W2603538695A5005496799 @default.
• W2603538695 hasAuthorship W2603538695A5014560783 @default.
• W2603538695 hasAuthorship W2603538695A5017632965 @default.
• W2603538695 hasAuthorship W2603538695A5045258788 @default.
• W2603538695 hasAuthorship W2603538695A5058371822 @default.
• W2603538695 hasBestOaLocation W26035386951 @default.
• W2603538695 hasConcept C126838900 @default.
• W2603538695 hasConcept C142724271 @default.
• W2603538695 hasConcept C143409427 @default.
• W2603538695 hasConcept C15744967 @default.
• W2603538695 hasConcept C169760540 @default.
• W2603538695 hasConcept C2776228812 @default.
• W2603538695 hasConcept C2776286752 @default.
• W2603538695 hasConcept C2776477761 @default.
• W2603538695 hasConcept C2776936178 @default.
• W2603538695 hasConcept C2777470907 @default.
• W2603538695 hasConcept C2778187257 @default.
• W2603538695 hasConcept C2779134260 @default.
• W2603538695 hasConcept C2779226451 @default.
• W2603538695 hasConcept C2779246727 @default.
• W2603538695 hasConcept C2779483572 @default.
• W2603538695 hasConcept C2779714222 @default.
• W2603538695 hasConcept C2781172350 @default.
• W2603538695 hasConcept C2993858690 @default.
• W2603538695 hasConcept C529278444 @default.
• W2603538695 hasConcept C71924100 @default.
• W2603538695 hasConceptScore W2603538695C126838900 @default.
• W2603538695 hasConceptScore W2603538695C142724271 @default.
• W2603538695 hasConceptScore W2603538695C143409427 @default.
• W2603538695 hasConceptScore W2603538695C15744967 @default.
• W2603538695 hasConceptScore W2603538695C169760540 @default.
• W2603538695 hasConceptScore W2603538695C2776228812 @default.
• W2603538695 hasConceptScore W2603538695C2776286752 @default.
• W2603538695 hasConceptScore W2603538695C2776477761 @default.
• W2603538695 hasConceptScore W2603538695C2776936178 @default.

• next