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• W2603669228 abstract "This study measured the antiplasmodial activity of nine zinc-dipicolylamine (ZnDPA) complexes against three strains of Plasmodium falciparum, the causative parasite of malaria. Growth inhibition assays showed significant activity against all tested strains, with 50% inhibitory concentrations between 5 and 600nM and almost no toxic effect against host cells including healthy red blood cells. Fluorescence microscopy studies with a green-fluorescent ZnDPA probe showed selective targeting of infected red blood cells. The results suggest that ZnDPA coordination complexes are promising antiplasmodial agents with potential for targeted malaria treatment." @default.
• W2603669228 created "2017-04-07" @default.
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• W2603669228 date "2017-05-01" @default.
• W2603669228 modified "2023-10-17" @default.
• W2603669228 title "Antiplasmodial activity of targeted zinc(II)-dipicolylamine complexes" @default.
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• W2603669228 doi "https://doi.org/10.1016/j.bmc.2017.03.050" @default.
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