FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2604208305> ?p ?o ?g. }

• W2604208305 endingPage "126.e1" @default.
• W2604208305 startingPage "119" @default.
• W2604208305 abstract "To determine whether prophylactic indomethacin (PINDO) has more or less morbidity than delayed conservative management of the moderate-to-large patent ductus arteriosus (PDA).We performed a prospective double cohort controlled study of infants delivered at ≤276/7 weeks gestation (n = 397). From January 2005 through April 2011, all infants were treated with PINDO (n = 247). From May 2011 through August 2016, no infant was treated with indomethacin until at least 8 postnatal days (conservative epoch, n = 150). Echocardiograms were performed on day 7 and at planned intervals until the PDA was small or closed. A single neonatologist prospectively collected all data.The incidence of moderate-to-large PDA on day 7 and duration of exposure to moderate-to-large PDA were significantly less in the PINDO epoch (incidence = 10%, median = 2 days) than the conservative epoch (incidence = 67%, median = 14 days). Ligation rates were low in both epochs (PINDO = 14%, conservative = 5%). In multivariate analyses, PINDO infants had a significantly lower incidence of bronchopulmonary dysplasia (BPD) (risk ratio = 0.68, CI: 0.46-0.89) and BPD or death (risk ratio= 0.78, CI: 0.62-0.95) than conservative infants. There were no differences between the epochs in death, intraventricular hemorrhage grades 3 and 4, necrotizing enterocolitis, or retinopathy of prematurity receiving treatment. The effects of PINDO on BPD and BPD or death were no longer significant when analyses were adjusted for presence of a moderate-to-large PDA on day 7. The significant effects of PINDO were independent of whether or not a ligation was performed.PINDO decreases BPD and BPD or death compared with delayed conservative PDA management. These effects are mediated by closure of the PDA." @default.
• W2604208305 created "2017-04-14" @default.
• W2604208305 creator A5001960805 @default.
• W2604208305 creator A5029324048 @default.
• W2604208305 date "2017-08-01" @default.
• W2604208305 modified "2023-10-16" @default.
• W2604208305 title "Prophylactic Indomethacin Compared with Delayed Conservative Management of the Patent Ductus Arteriosus in Extremely Preterm Infants: Effects on Neonatal Outcomes" @default.
• W2604208305 cites W1578545245 @default.
• W2604208305 cites W1857797615 @default.
• W2604208305 cites W1957857943 @default.
• W2604208305 cites W1966463178 @default.
• W2604208305 cites W1990085582 @default.
• W2604208305 cites W2003552355 @default.
• W2604208305 cites W2008903650 @default.
• W2604208305 cites W2019549525 @default.
• W2604208305 cites W2022878856 @default.
• W2604208305 cites W2044755112 @default.
• W2604208305 cites W2046224781 @default.
• W2604208305 cites W2047142537 @default.
• W2604208305 cites W2048815495 @default.
• W2604208305 cites W2052035853 @default.
• W2604208305 cites W2056315262 @default.
• W2604208305 cites W2060742830 @default.
• W2604208305 cites W2063995081 @default.
• W2604208305 cites W2067861387 @default.
• W2604208305 cites W2071321750 @default.
• W2604208305 cites W2082605022 @default.
• W2604208305 cites W2086560570 @default.
• W2604208305 cites W2100301614 @default.
• W2604208305 cites W2113606273 @default.
• W2604208305 cites W2114604788 @default.
• W2604208305 cites W2117425969 @default.
• W2604208305 cites W2144343958 @default.
• W2604208305 cites W2164964624 @default.
• W2604208305 cites W2180557034 @default.
• W2604208305 cites W2283482432 @default.
• W2604208305 cites W2296316750 @default.
• W2604208305 cites W2329099508 @default.
• W2604208305 cites W2498134373 @default.
• W2604208305 cites W2523726039 @default.
• W2604208305 cites W2558452517 @default.
• W2604208305 cites W2562522559 @default.
• W2604208305 cites W2221853565 @default.
• W2604208305 doi "https://doi.org/10.1016/j.jpeds.2017.03.021" @default.
• W2604208305 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5533630" @default.
• W2604208305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28396025" @default.
• W2604208305 hasPublicationYear "2017" @default.
• W2604208305 type Work @default.
• W2604208305 sameAs 2604208305 @default.
• W2604208305 citedByCount "77" @default.
• W2604208305 countsByYear W26042083052017 @default.
• W2604208305 countsByYear W26042083052018 @default.
• W2604208305 countsByYear W26042083052019 @default.
• W2604208305 countsByYear W26042083052020 @default.
• W2604208305 countsByYear W26042083052021 @default.
• W2604208305 countsByYear W26042083052022 @default.
• W2604208305 countsByYear W26042083052023 @default.
• W2604208305 crossrefType "journal-article" @default.
• W2604208305 hasAuthorship W2604208305A5001960805 @default.
• W2604208305 hasAuthorship W2604208305A5029324048 @default.
• W2604208305 hasBestOaLocation W26042083052 @default.
• W2604208305 hasConcept C120665830 @default.
• W2604208305 hasConcept C121332964 @default.
• W2604208305 hasConcept C141071460 @default.
• W2604208305 hasConcept C187212893 @default.
• W2604208305 hasConcept C188816634 @default.
• W2604208305 hasConcept C2778376644 @default.
• W2604208305 hasConcept C2778721537 @default.
• W2604208305 hasConcept C2779234561 @default.
• W2604208305 hasConcept C2779252433 @default.
• W2604208305 hasConcept C2779303187 @default.
• W2604208305 hasConcept C2779918416 @default.
• W2604208305 hasConcept C2780904754 @default.
• W2604208305 hasConcept C2781236024 @default.
• W2604208305 hasConcept C46973012 @default.
• W2604208305 hasConcept C536800656 @default.
• W2604208305 hasConcept C54355233 @default.
• W2604208305 hasConcept C61511704 @default.
• W2604208305 hasConcept C71924100 @default.
• W2604208305 hasConcept C86803240 @default.
• W2604208305 hasConceptScore W2604208305C120665830 @default.
• W2604208305 hasConceptScore W2604208305C121332964 @default.
• W2604208305 hasConceptScore W2604208305C141071460 @default.
• W2604208305 hasConceptScore W2604208305C187212893 @default.
• W2604208305 hasConceptScore W2604208305C188816634 @default.
• W2604208305 hasConceptScore W2604208305C2778376644 @default.
• W2604208305 hasConceptScore W2604208305C2778721537 @default.
• W2604208305 hasConceptScore W2604208305C2779234561 @default.
• W2604208305 hasConceptScore W2604208305C2779252433 @default.
• W2604208305 hasConceptScore W2604208305C2779303187 @default.
• W2604208305 hasConceptScore W2604208305C2779918416 @default.
• W2604208305 hasConceptScore W2604208305C2780904754 @default.
• W2604208305 hasConceptScore W2604208305C2781236024 @default.
• W2604208305 hasConceptScore W2604208305C46973012 @default.
• W2604208305 hasConceptScore W2604208305C536800656 @default.
• W2604208305 hasConceptScore W2604208305C54355233 @default.
• W2604208305 hasConceptScore W2604208305C61511704 @default.
• W2604208305 hasConceptScore W2604208305C71924100 @default.

• next