Matches in SemOpenAlex for { <https://semopenalex.org/work/W2604440916> ?p ?o ?g. }
- W2604440916 abstract "Atypical enteropathogenic Escherichia coli (aEPEC) strains are emerging enteropathogens that have been detected worldwide. A collection of 228 aEPEC strains (121 from diarrheal patients, 27 from healthy carriers, 47 from animals and 33 from raw meats) were investigated for serotypes, virulence gene profiles and phylogenetic relationships. Sixty-six O serogroups were identified. For the 20 virulence genes detected, statistically significant differences were observed in the overall prevalence of efa1 (lifA), nleB, nleE, set/ent, paa and ehxA genes among strains from diarrheal patients, healthy carriers, animals and raw meats, respectively. Strains from diarrheal patients had significantly higher levels of efa1 (lifA) (29.8% vs. 0, P = 0.0002), nleB (41.3% vs. 7.4%, P = 0.0004), nleE (43.8% vs. 7.4%, P = 0.0002) and set/ent (41.3% vs. 7.4%, P = 0.0004) genes than strains obtained from healthy carriers. The paa gene was identified more often in isolates from raw meats (63.6% vs. 14.8%, P < 0.0001), animals (42.6% vs. 14.8%, P < 0.0122), and diarrheal patients (36.4% vs. 14.8%, P < 0.0225) than in strains obtained from healthy carriers. The ehxA gene was detected more frequently in strains from raw meats than in strains from diarrheal patients (27.3% vs. 2.5%, P = 0.0000) and healthy carriers (27.3% vs. 7.4%, P = 0.0474). The phylogenetic marker, yjaA, was more frequently observed in strains among healthy carriers than in diarrheal patient strains. Among the 228 aEPEC strains, 79 sequence types (STs) were identified. The prominent STs, which comprised strains carrying the four OI-122 genes and lpfA, were ST40, ST328, and ST29. Overall, the results indicate that aEPEC strains isolated in China are highly heterogeneous. aEPEC strains that are potentially more pathogenic appear to be related to specific STs or clonal complexes and serotypes. The high prevalence of diarrhea-associated genes in animal or raw meat strains suggests a zoonotic transmission pathway for potentially human pathogenic aEPEC." @default.
- W2604440916 created "2017-04-14" @default.
- W2604440916 creator A5003007348 @default.
- W2604440916 creator A5033281929 @default.
- W2604440916 creator A5042274161 @default.
- W2604440916 creator A5043402436 @default.
- W2604440916 creator A5072502783 @default.
- W2604440916 creator A5075196242 @default.
- W2604440916 creator A5076976370 @default.
- W2604440916 creator A5081386855 @default.
- W2604440916 creator A5088139903 @default.
- W2604440916 date "2017-04-04" @default.
- W2604440916 modified "2023-10-02" @default.
- W2604440916 title "High Prevalence of Virulence Genes in Specific Genotypes of Atypical Enteropathogenic Escherichia coli" @default.
- W2604440916 cites W1512874345 @default.
- W2604440916 cites W1661595674 @default.
- W2604440916 cites W1774638989 @default.
- W2604440916 cites W1803487872 @default.
- W2604440916 cites W1961504819 @default.
- W2604440916 cites W1968641728 @default.
- W2604440916 cites W1982653769 @default.
- W2604440916 cites W1983147020 @default.
- W2604440916 cites W1986255967 @default.
- W2604440916 cites W2003076157 @default.
- W2604440916 cites W2014098779 @default.
- W2604440916 cites W2014298338 @default.
- W2604440916 cites W2027493889 @default.
- W2604440916 cites W2037340333 @default.
- W2604440916 cites W2060727173 @default.
- W2604440916 cites W2082508094 @default.
- W2604440916 cites W2090855088 @default.
- W2604440916 cites W2091342108 @default.
- W2604440916 cites W2091926133 @default.
- W2604440916 cites W2099654729 @default.
- W2604440916 cites W2108894780 @default.
- W2604440916 cites W2109764507 @default.
- W2604440916 cites W2111782347 @default.
- W2604440916 cites W2113230410 @default.
- W2604440916 cites W2113742716 @default.
- W2604440916 cites W2114053580 @default.
- W2604440916 cites W2116652997 @default.
- W2604440916 cites W2121695290 @default.
- W2604440916 cites W2125339057 @default.
- W2604440916 cites W2125789964 @default.
- W2604440916 cites W2128611507 @default.
- W2604440916 cites W2130278011 @default.
- W2604440916 cites W2130661777 @default.
- W2604440916 cites W2137252923 @default.
- W2604440916 cites W2138738692 @default.
- W2604440916 cites W2145012506 @default.
- W2604440916 cites W2146297863 @default.
- W2604440916 cites W2146377128 @default.
- W2604440916 cites W2146869978 @default.
- W2604440916 cites W2148120451 @default.
- W2604440916 cites W2148912198 @default.
- W2604440916 cites W2150066155 @default.
- W2604440916 cites W2152019335 @default.
- W2604440916 cites W2158755273 @default.
- W2604440916 cites W2159153498 @default.
- W2604440916 cites W2161744554 @default.
- W2604440916 cites W2165065438 @default.
- W2604440916 cites W2166817179 @default.
- W2604440916 cites W2168375716 @default.
- W2604440916 cites W2170555862 @default.
- W2604440916 cites W2179033777 @default.
- W2604440916 cites W2317742173 @default.
- W2604440916 cites W2341787842 @default.
- W2604440916 cites W2342507485 @default.
- W2604440916 cites W2348137775 @default.
- W2604440916 cites W2413292059 @default.
- W2604440916 cites W2428397506 @default.
- W2604440916 cites W2140605079 @default.
- W2604440916 doi "https://doi.org/10.3389/fcimb.2017.00109" @default.
- W2604440916 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5378719" @default.
- W2604440916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28421169" @default.
- W2604440916 hasPublicationYear "2017" @default.
- W2604440916 type Work @default.
- W2604440916 sameAs 2604440916 @default.
- W2604440916 citedByCount "26" @default.
- W2604440916 countsByYear W26044409162017 @default.
- W2604440916 countsByYear W26044409162018 @default.
- W2604440916 countsByYear W26044409162019 @default.
- W2604440916 countsByYear W26044409162020 @default.
- W2604440916 countsByYear W26044409162021 @default.
- W2604440916 countsByYear W26044409162022 @default.
- W2604440916 countsByYear W26044409162023 @default.
- W2604440916 crossrefType "journal-article" @default.
- W2604440916 hasAuthorship W2604440916A5003007348 @default.
- W2604440916 hasAuthorship W2604440916A5033281929 @default.
- W2604440916 hasAuthorship W2604440916A5042274161 @default.
- W2604440916 hasAuthorship W2604440916A5043402436 @default.
- W2604440916 hasAuthorship W2604440916A5072502783 @default.
- W2604440916 hasAuthorship W2604440916A5075196242 @default.
- W2604440916 hasAuthorship W2604440916A5076976370 @default.
- W2604440916 hasAuthorship W2604440916A5081386855 @default.
- W2604440916 hasAuthorship W2604440916A5088139903 @default.
- W2604440916 hasBestOaLocation W26044409161 @default.
- W2604440916 hasConcept C10389963 @default.
- W2604440916 hasConcept C104317684 @default.
- W2604440916 hasConcept C126322002 @default.