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- W2604449501 startingPage "118" @default.
- W2604449501 abstract "Systemic lupus erythematosus (SLE) is a chronic inflammatory and autoimmune disease characterised by multiple organ involvement and a large number of complications. SLE management remains complicated owing to the biological heterogeneity between patients and the lack of safe and specific targeted therapies. There is evidence that dietary factors can contribute to the geoepidemiology of autoimmune diseases such as SLE. Thus, diet therapy could be a promising approach in SLE owing to both its potential prophylactic effects, without the side effects of classical pharmacology, and its contribution to reducing co-morbidities and improving quality of life in patients with SLE. However, the question arises as to whether nutrients could ameliorate or exacerbate SLE and how they could modulate inflammation and immune function at a molecular level. The present review summarises preclinical and clinical experiences to provide the reader with an update of the positive and negative aspects of macro- and micronutrients and other nutritional factors, including dietary phenols, on SLE, focusing on the mechanisms of action involved." @default.
- W2604449501 created "2017-04-14" @default.
- W2604449501 creator A5038291122 @default.
- W2604449501 creator A5074750600 @default.
- W2604449501 creator A5091038654 @default.
- W2604449501 date "2017-03-15" @default.
- W2604449501 modified "2023-10-18" @default.
- W2604449501 title "An update on diet and nutritional factors in systemic lupus erythematosus management" @default.
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