FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2604632698> ?p ?o ?g. }

• W2604632698 endingPage "225" @default.
• W2604632698 startingPage "216" @default.
• W2604632698 abstract "Azole-resistant aspergillosis in high-risk patients with hematological malignancy or hematopoietic stem cell transplantation (HSCT) is a cause of concern.We examined changes over time in triazole minimum inhibitory concentrations (MICs) of 290 sequential Aspergillus isolates recovered from respiratory sources during 1999-2002 (before introduction of the Aspergillus-potent triazoles voriconazole and posaconazole) and 2003-2015 at MD Anderson Cancer Center. We also tested for polymorphisms in ergosterol biosynthetic genes (cyp51A, erg3C, erg1) in the 37 Aspergillus fumigatus isolates isolated from both periods that had non-wild-type (WT) MICs. For the 107 patients with hematologic cancer and/or HSCT with invasive pulmonary aspergillosis, we correlated in vitro susceptibility with 42-day mortality.Non-WT MICs were found in 37 (13%) isolates and was only low level (MIC <8 mg/L) in all isolates. Higher-triazole MICs were more frequent in the second period and were Aspergillus-species specific, and only encountered in A. fumigatus. No polymorphisms in cyp51A, erg3C, erg1 genes were identified. There was no correlation between in vitro MICs with 42-day mortality in patients with invasive pulmonary aspergillosis, irrespective of antifungal treatment. Asian race (odds ratio [OR], 20.9; 95% confidence interval [CI], 2.5-173.5; P = .005) and azole exposure in the prior 3 months (OR, 9.6; 95% CI, 1.9-48.5; P = .006) were associated with azole resistance.Non-WT azole MICs in Aspergillus are increasing and this is associated with prior azole exposure in patients with hematologic cancer or HSCT. However, no correlation of MIC with outcome of aspergillosis was found in our patient cohort." @default.
• W2604632698 created "2017-04-14" @default.
• W2604632698 creator A5005383633 @default.
• W2604632698 creator A5007730121 @default.
• W2604632698 creator A5024606224 @default.
• W2604632698 creator A5041039527 @default.
• W2604632698 creator A5043677430 @default.
• W2604632698 creator A5052550074 @default.
• W2604632698 creator A5059620644 @default.
• W2604632698 creator A5063345553 @default.
• W2604632698 creator A5066067579 @default.
• W2604632698 creator A5066166630 @default.
• W2604632698 creator A5073811029 @default.
• W2604632698 creator A5075401784 @default.
• W2604632698 creator A5076294031 @default.
• W2604632698 date "2017-03-31" @default.
• W2604632698 modified "2023-10-01" @default.
• W2604632698 title "Changes in In Vitro Susceptibility Patterns of Aspergillus to Triazoles and Correlation With Aspergillosis Outcome in a Tertiary Care Cancer Center, 1999–2015" @default.
• W2604632698 cites W1486160699 @default.
• W2604632698 cites W1832443905 @default.
• W2604632698 cites W1889182392 @default.
• W2604632698 cites W2050335832 @default.
• W2604632698 cites W2062983075 @default.
• W2604632698 cites W2066649608 @default.
• W2604632698 cites W2093588169 @default.
• W2604632698 cites W2105687042 @default.
• W2604632698 cites W2110459852 @default.
• W2604632698 cites W2114168745 @default.
• W2604632698 cites W2121353031 @default.
• W2604632698 cites W2121353759 @default.
• W2604632698 cites W2135182325 @default.
• W2604632698 cites W2137693232 @default.
• W2604632698 cites W2138186956 @default.
• W2604632698 cites W2162022529 @default.
• W2604632698 cites W2166734004 @default.
• W2604632698 cites W2166972217 @default.
• W2604632698 cites W2169748580 @default.
• W2604632698 cites W2170027173 @default.
• W2604632698 cites W2200750055 @default.
• W2604632698 cites W2336840435 @default.
• W2604632698 cites W2337464793 @default.
• W2604632698 cites W2515591485 @default.
• W2604632698 cites W2518812025 @default.
• W2604632698 cites W2555615372 @default.
• W2604632698 doi "https://doi.org/10.1093/cid/cix297" @default.
• W2604632698 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5850538" @default.
• W2604632698 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28379304" @default.
• W2604632698 hasPublicationYear "2017" @default.
• W2604632698 type Work @default.
• W2604632698 sameAs 2604632698 @default.
• W2604632698 citedByCount "49" @default.
• W2604632698 countsByYear W26046326982017 @default.
• W2604632698 countsByYear W26046326982018 @default.
• W2604632698 countsByYear W26046326982019 @default.
• W2604632698 countsByYear W26046326982020 @default.
• W2604632698 countsByYear W26046326982021 @default.
• W2604632698 countsByYear W26046326982022 @default.
• W2604632698 countsByYear W26046326982023 @default.
• W2604632698 crossrefType "journal-article" @default.
• W2604632698 hasAuthorship W2604632698A5005383633 @default.
• W2604632698 hasAuthorship W2604632698A5007730121 @default.
• W2604632698 hasAuthorship W2604632698A5024606224 @default.
• W2604632698 hasAuthorship W2604632698A5041039527 @default.
• W2604632698 hasAuthorship W2604632698A5043677430 @default.
• W2604632698 hasAuthorship W2604632698A5052550074 @default.
• W2604632698 hasAuthorship W2604632698A5059620644 @default.
• W2604632698 hasAuthorship W2604632698A5063345553 @default.
• W2604632698 hasAuthorship W2604632698A5066067579 @default.
• W2604632698 hasAuthorship W2604632698A5066166630 @default.
• W2604632698 hasAuthorship W2604632698A5073811029 @default.
• W2604632698 hasAuthorship W2604632698A5075401784 @default.
• W2604632698 hasAuthorship W2604632698A5076294031 @default.
• W2604632698 hasBestOaLocation W26046326981 @default.
• W2604632698 hasConcept C121608353 @default.
• W2604632698 hasConcept C126322002 @default.
• W2604632698 hasConcept C156957248 @default.
• W2604632698 hasConcept C203014093 @default.
• W2604632698 hasConcept C2776391196 @default.
• W2604632698 hasConcept C2778566413 @default.
• W2604632698 hasConcept C2779175654 @default.
• W2604632698 hasConcept C2779548794 @default.
• W2604632698 hasConcept C2779787849 @default.
• W2604632698 hasConcept C2780315139 @default.
• W2604632698 hasConcept C2780651595 @default.
• W2604632698 hasConcept C2780690907 @default.
• W2604632698 hasConcept C71924100 @default.
• W2604632698 hasConcept C86803240 @default.
• W2604632698 hasConcept C89423630 @default.
• W2604632698 hasConcept C90924648 @default.
• W2604632698 hasConceptScore W2604632698C121608353 @default.
• W2604632698 hasConceptScore W2604632698C126322002 @default.
• W2604632698 hasConceptScore W2604632698C156957248 @default.
• W2604632698 hasConceptScore W2604632698C203014093 @default.
• W2604632698 hasConceptScore W2604632698C2776391196 @default.
• W2604632698 hasConceptScore W2604632698C2778566413 @default.
• W2604632698 hasConceptScore W2604632698C2779175654 @default.
• W2604632698 hasConceptScore W2604632698C2779548794 @default.
• W2604632698 hasConceptScore W2604632698C2779787849 @default.

• next