Matches in SemOpenAlex for { <https://semopenalex.org/work/W2604704361> ?p ?o ?g. }
- W2604704361 endingPage "33" @default.
- W2604704361 startingPage "23" @default.
- W2604704361 abstract "IFN-α is the only treatment capable of inducing long-term remission in some patients with ocular Behçet's disease. In this review, we focus on immune mechanisms of IFN-α in animal models and patients and compare the outcome of different clinical studies.Review of literature using PubMed and Google and original data from rat models with monophasic/chronic or relapsing experimental autoimmune uveitis treated with IFN-α.The role of IFN-α and its effect on various cell types were investigated, in some cases with contradictory results. Some patients respond very well to IFN-α treatment, while others are non-responders, which was reflected in the uveitis rat models: relapsing uveitis was ameliorated, the monophasic/chronic disease even aggravated.Despite intensive investigations in patients and animal models, the immune mechanisms explaining the therapeutic effect of IFN-α in ocular Behçet's disease are not yet fully understood and need further investigation." @default.
- W2604704361 created "2017-04-14" @default.
- W2604704361 creator A5006518596 @default.
- W2604704361 creator A5043267366 @default.
- W2604704361 creator A5077859270 @default.
- W2604704361 date "2017-04-04" @default.
- W2604704361 modified "2023-09-26" @default.
- W2604704361 title "The Role of IFN-alpha in Experimental and Clinical Uveitis" @default.
- W2604704361 cites W1499740654 @default.
- W2604704361 cites W1524785835 @default.
- W2604704361 cites W1542058436 @default.
- W2604704361 cites W1592560415 @default.
- W2604704361 cites W1897524591 @default.
- W2604704361 cites W1964372332 @default.
- W2604704361 cites W1972298566 @default.
- W2604704361 cites W1981144318 @default.
- W2604704361 cites W1981651463 @default.
- W2604704361 cites W1983951850 @default.
- W2604704361 cites W1988413772 @default.
- W2604704361 cites W1999083645 @default.
- W2604704361 cites W2002696122 @default.
- W2604704361 cites W2002712630 @default.
- W2604704361 cites W2008345204 @default.
- W2604704361 cites W2009407931 @default.
- W2604704361 cites W2017332368 @default.
- W2604704361 cites W2018008269 @default.
- W2604704361 cites W2021372623 @default.
- W2604704361 cites W2023536389 @default.
- W2604704361 cites W2033782014 @default.
- W2604704361 cites W2033947371 @default.
- W2604704361 cites W2035677339 @default.
- W2604704361 cites W2037843125 @default.
- W2604704361 cites W2038670415 @default.
- W2604704361 cites W2040235283 @default.
- W2604704361 cites W2042087027 @default.
- W2604704361 cites W2045165663 @default.
- W2604704361 cites W2049323177 @default.
- W2604704361 cites W2049584106 @default.
- W2604704361 cites W2052150279 @default.
- W2604704361 cites W2053017103 @default.
- W2604704361 cites W2060913403 @default.
- W2604704361 cites W2060926084 @default.
- W2604704361 cites W2063403309 @default.
- W2604704361 cites W2063515596 @default.
- W2604704361 cites W2068697839 @default.
- W2604704361 cites W2076156048 @default.
- W2604704361 cites W2081147074 @default.
- W2604704361 cites W2085237060 @default.
- W2604704361 cites W2086017493 @default.
- W2604704361 cites W2086438994 @default.
- W2604704361 cites W2086880284 @default.
- W2604704361 cites W2091622667 @default.
- W2604704361 cites W2093395242 @default.
- W2604704361 cites W2093707774 @default.
- W2604704361 cites W2097385117 @default.
- W2604704361 cites W2098038280 @default.
- W2604704361 cites W2099200878 @default.
- W2604704361 cites W2102047778 @default.
- W2604704361 cites W2104040734 @default.
- W2604704361 cites W2108849101 @default.
- W2604704361 cites W2113666356 @default.
- W2604704361 cites W2114465053 @default.
- W2604704361 cites W2115483836 @default.
- W2604704361 cites W2118079267 @default.
- W2604704361 cites W2119847512 @default.
- W2604704361 cites W2120390079 @default.
- W2604704361 cites W2121119865 @default.
- W2604704361 cites W2124807171 @default.
- W2604704361 cites W2132932119 @default.
- W2604704361 cites W2134579230 @default.
- W2604704361 cites W2142081323 @default.
- W2604704361 cites W2144652247 @default.
- W2604704361 cites W2151224106 @default.
- W2604704361 cites W2152068912 @default.
- W2604704361 cites W2170726975 @default.
- W2604704361 cites W2209156328 @default.
- W2604704361 cites W2261930191 @default.
- W2604704361 cites W2298863506 @default.
- W2604704361 cites W2320935413 @default.
- W2604704361 cites W2417691318 @default.
- W2604704361 cites W326172054 @default.
- W2604704361 cites W4245315848 @default.
- W2604704361 cites W4312850899 @default.
- W2604704361 cites W953970739 @default.
- W2604704361 doi "https://doi.org/10.1080/09273948.2017.1298822" @default.
- W2604704361 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28375033" @default.
- W2604704361 hasPublicationYear "2017" @default.
- W2604704361 type Work @default.
- W2604704361 sameAs 2604704361 @default.
- W2604704361 citedByCount "7" @default.
- W2604704361 countsByYear W26047043612020 @default.
- W2604704361 countsByYear W26047043612021 @default.
- W2604704361 countsByYear W26047043612022 @default.
- W2604704361 countsByYear W26047043612023 @default.
- W2604704361 crossrefType "journal-article" @default.
- W2604704361 hasAuthorship W2604704361A5006518596 @default.
- W2604704361 hasAuthorship W2604704361A5043267366 @default.
- W2604704361 hasAuthorship W2604704361A5077859270 @default.