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- W2604762024 abstract "We examined D2-dopamine receptor containing neurons in cultures of neonatal rat striatum for apoptosis following dopamine treatment. Exposure to cultures to micromolar concentrations of dopamine resulted in 60–70% killing of D2-dopamine receptor neurons within 24 hr. We also utilized a double labeling procedure to determine that treatment with dopamine induced apoptosis in D2-dopamine receptor containing neurons. These results suggest that loss of D2-dopamine receptor containing neurons during aging could be due to an apoptotic effect of dopamine. J. Neurosci. Res. 47:393–399, 1997. © 1997 Wiley-Liss, Inc. 1 This article is a US Government work and, as such, is in the public domain in the United States of America." @default.
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- W2604762024 date "1997-02-15" @default.
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- W2604762024 title "Dopamine induces apoptosis in cultured rat striatal neurons; possible mechanism of D2‐dopamine receptor neuron loss during aging" @default.
- W2604762024 doi "https://doi.org/10.1002/(sici)1097-4547(19970215)47:4<393::aid-jnr4>3.3.co;2-l" @default.
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