FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2604813206> ?p ?o ?g. }

• W2604813206 abstract "Mycobacterium abscessus represents an important respiratory pathogen among the rapidly-growing non-tuberculous mycobacteria. Infections caused by M. abscessus are increasingly found in cystic fibrosis patients and are often refractory to antibiotic therapy. The underlying immunopathological mechanisms of pathogenesis remain largely unknown. A major reason for the poor advances in M. abscessus research has been a lack of adequate models to study the acute and chronic stages of the disease leading to delayed progress of evaluation of therapeutic efficacy of potentially active antibiotics. However, the recent development of cellular models led to new insights in the interplay between M. abscessus with host macrophages as well as with amoebae, proposed to represent the environmental host and reservoir for non-tuberculous mycobacteria. The zebrafish embryo has also appeared as a useful alternative to more traditional models as it recapitulates the vertebrate immune system and, due to its optical transparency, allows a spatio-temporal visualization of the infection process in a living animal. More sophisticated immunocompromised mice have also been exploited recently to dissect the immune and inflammatory responses to M. abscessus. Herein, we will discuss the limitations, advantages and potential offered by these various models to study the pathophysiology of M. abscessus infection and to assess the preclinical efficacy of compounds active against this emerging human pathogen." @default.
• W2604813206 created "2017-04-14" @default.
• W2604813206 creator A5027988741 @default.
• W2604813206 creator A5029558296 @default.
• W2604813206 creator A5056305582 @default.
• W2604813206 creator A5066987157 @default.
• W2604813206 date "2017-04-04" @default.
• W2604813206 modified "2023-10-12" @default.
• W2604813206 title "The Diverse Cellular and Animal Models to Decipher the Physiopathological Traits of Mycobacterium abscessus Infection" @default.
• W2604813206 cites W1418640045 @default.
• W2604813206 cites W1908290270 @default.
• W2604813206 cites W1990733959 @default.
• W2604813206 cites W1990886455 @default.
• W2604813206 cites W1998111707 @default.
• W2604813206 cites W2007473864 @default.
• W2604813206 cites W2016283787 @default.
• W2604813206 cites W2020866550 @default.
• W2604813206 cites W2022562233 @default.
• W2604813206 cites W2026584118 @default.
• W2604813206 cites W2034064528 @default.
• W2604813206 cites W2050697866 @default.
• W2604813206 cites W2070440819 @default.
• W2604813206 cites W2073366489 @default.
• W2604813206 cites W2074401088 @default.
• W2604813206 cites W2078178166 @default.
• W2604813206 cites W2085432374 @default.
• W2604813206 cites W2091442643 @default.
• W2604813206 cites W2099752190 @default.
• W2604813206 cites W2108347160 @default.
• W2604813206 cites W2108459792 @default.
• W2604813206 cites W2116780041 @default.
• W2604813206 cites W2119462342 @default.
• W2604813206 cites W2125725259 @default.
• W2604813206 cites W2136827246 @default.
• W2604813206 cites W2141115207 @default.
• W2604813206 cites W2143540026 @default.
• W2604813206 cites W2145880721 @default.
• W2604813206 cites W2150214731 @default.
• W2604813206 cites W2150573104 @default.
• W2604813206 cites W2151082827 @default.
• W2604813206 cites W2154265102 @default.
• W2604813206 cites W2154315671 @default.
• W2604813206 cites W2157752583 @default.
• W2604813206 cites W2159507770 @default.
• W2604813206 cites W2163379826 @default.
• W2604813206 cites W2164474259 @default.
• W2604813206 cites W2167468135 @default.
• W2604813206 cites W2167597232 @default.
• W2604813206 cites W2167703036 @default.
• W2604813206 cites W2168036009 @default.
• W2604813206 cites W2168348711 @default.
• W2604813206 cites W2171981522 @default.
• W2604813206 cites W2262886786 @default.
• W2604813206 cites W2342849480 @default.
• W2604813206 cites W2469803725 @default.
• W2604813206 cites W2479871546 @default.
• W2604813206 cites W2492237845 @default.
• W2604813206 cites W2495237884 @default.
• W2604813206 cites W2511213199 @default.
• W2604813206 cites W2529180302 @default.
• W2604813206 cites W2529696598 @default.
• W2604813206 cites W2547347442 @default.
• W2604813206 cites W2553168732 @default.
• W2604813206 cites W2558222949 @default.
• W2604813206 cites W2571802386 @default.
• W2604813206 doi "https://doi.org/10.3389/fcimb.2017.00100" @default.
• W2604813206 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5378707" @default.
• W2604813206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28421165" @default.
• W2604813206 hasPublicationYear "2017" @default.
• W2604813206 type Work @default.
• W2604813206 sameAs 2604813206 @default.
• W2604813206 citedByCount "57" @default.
• W2604813206 countsByYear W26048132062017 @default.
• W2604813206 countsByYear W26048132062018 @default.
• W2604813206 countsByYear W26048132062019 @default.
• W2604813206 countsByYear W26048132062020 @default.
• W2604813206 countsByYear W26048132062021 @default.
• W2604813206 countsByYear W26048132062022 @default.
• W2604813206 countsByYear W26048132062023 @default.
• W2604813206 crossrefType "journal-article" @default.
• W2604813206 hasAuthorship W2604813206A5027988741 @default.
• W2604813206 hasAuthorship W2604813206A5029558296 @default.
• W2604813206 hasAuthorship W2604813206A5056305582 @default.
• W2604813206 hasAuthorship W2604813206A5066987157 @default.
• W2604813206 hasBestOaLocation W26048132061 @default.
• W2604813206 hasConcept C104317684 @default.
• W2604813206 hasConcept C142724271 @default.
• W2604813206 hasConcept C203014093 @default.
• W2604813206 hasConcept C2776111603 @default.
• W2604813206 hasConcept C2776460866 @default.
• W2604813206 hasConcept C2776878037 @default.
• W2604813206 hasConcept C2776938444 @default.
• W2604813206 hasConcept C2778679867 @default.
• W2604813206 hasConcept C2779134260 @default.
• W2604813206 hasConcept C2780374374 @default.
• W2604813206 hasConcept C2781069245 @default.
• W2604813206 hasConcept C501593827 @default.
• W2604813206 hasConcept C54355233 @default.
• W2604813206 hasConcept C55493867 @default.
• W2604813206 hasConcept C71924100 @default.

• next