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- W2604892020 abstract "797 Background: Single agent therapy with Capecitabine demonstrates a good activity, tolerability and efficacy in many solid tumors. Due to its particular mechanism of action and its oral administration, it is an attractive alternative for the palliative treatment on elderly breast cancer patients. Methods: To evaluate the toxicity and efficacy of capecitabine monotherapy in elderly patients with metastatic breast cancer. Secondary endpoint was time to progression. 63 patients were included between January 2001 -December 2002. The median age was 70 years, range 65–78. Patients could had prior chemotherapy and/or hormonotherapy, not for metastatic disease. All patients had measurable or evaluable disease. Performance status was ECOG 0–2. They had adequate bone marrow, renal, hepatic and cardiac functions. The metastatic sites were: liver -27, lung -19, bone -35, soft tissue -17, lymph nodes -11 and pleura -9 patients. There were no brain metastases in the study group. Treatment schedule: Capecitabine 1250 ..." @default.
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- W2604892020 date "2004-07-15" @default.
- W2604892020 modified "2023-09-26" @default.
- W2604892020 title "Capecitabine monotherapy for elderly patients with metastatic breast cancer" @default.
- W2604892020 doi "https://doi.org/10.1200/jco.2004.22.14_suppl.797" @default.
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