Matches in SemOpenAlex for { <https://semopenalex.org/work/W2604927440> ?p ?o ?g. }
Showing items 1 to 54 of
54
with 100 items per page.
- W2604927440 abstract "6569 Background: Although blacks have a lower risk of non-Hodgkin lymphoma (NHL) compared to whites, black non-Hodgkin lymphoma (NHL) patients experience worse survival than white patients. This study aims to examine in patients with diffuse large B-cell lymphoma (DLBCL), the most common subtype of NHL, how much of the racial disparity in survival can be explained by differences in certain demographic (age, sex and area-level education) and access-to-care-related (stage, treatment, health insurance status) factors. Methods: Our cohort included 3716 non-Hispanic white or black DLBCL patients aged 18-64, diagnosed in 2004-2005 from the National Cancer Database (NCDB), a nationwide, hospital-based cancer registry. The analysis included only HIV/AIDS-negative patients. Kaplan-Meier survival curves were drawn for blacks and whites. Cox proportional hazards model was fitted to estimate hazard ratios (HR) and the 95% confidence intervals (CI) for race with and without controlling for demographic factors (age, sex and area-level education), stage, treatment and health insurance status. Results: Black patients had a worse survival than white patients (5-year survival rate 66.6% in blacks vs. 73.3% in whites, log-rank test p-value = 0.0006). Without adjusting for other factors, blacks had a 34% higher risk of death compared to whites (crude HR=1.34, 95% CI =1.13-1.58). After adjusting for demographic factors including age, sex and area-level education, the HR reduced to 1.27 (95% CI=1.06-1.51). After further adjustment for stage, treatment and insurance status, the association disappeared (HR=1.03, 95% CI= 0.86-1.23). Conclusions: Demographic factors and access-to-care-related factors including stage, treatment and health insurance status fully explained the black-white racial disparity in DLBCL survival in this cohort. Our findings suggest that improvements towards timely diagnosis, appropriate treatment and other adequate access to health care measures could potentially eliminate the survival disparity between black and white DLBCL patients." @default.
- W2604927440 created "2017-04-14" @default.
- W2604927440 creator A5000024586 @default.
- W2604927440 creator A5009198168 @default.
- W2604927440 creator A5078728097 @default.
- W2604927440 date "2013-05-20" @default.
- W2604927440 modified "2023-09-28" @default.
- W2604927440 title "Racial disparity in diffuse large B-cell lymphoma survival." @default.
- W2604927440 doi "https://doi.org/10.1200/jco.2013.31.15_suppl.6569" @default.
- W2604927440 hasPublicationYear "2013" @default.
- W2604927440 type Work @default.
- W2604927440 sameAs 2604927440 @default.
- W2604927440 citedByCount "0" @default.
- W2604927440 crossrefType "journal-article" @default.
- W2604927440 hasAuthorship W2604927440A5000024586 @default.
- W2604927440 hasAuthorship W2604927440A5009198168 @default.
- W2604927440 hasAuthorship W2604927440A5078728097 @default.
- W2604927440 hasConcept C126322002 @default.
- W2604927440 hasConcept C143998085 @default.
- W2604927440 hasConcept C2778559949 @default.
- W2604927440 hasConcept C2779338263 @default.
- W2604927440 hasConcept C71924100 @default.
- W2604927440 hasConceptScore W2604927440C126322002 @default.
- W2604927440 hasConceptScore W2604927440C143998085 @default.
- W2604927440 hasConceptScore W2604927440C2778559949 @default.
- W2604927440 hasConceptScore W2604927440C2779338263 @default.
- W2604927440 hasConceptScore W2604927440C71924100 @default.
- W2604927440 hasLocation W26049274401 @default.
- W2604927440 hasOpenAccess W2604927440 @default.
- W2604927440 hasPrimaryLocation W26049274401 @default.
- W2604927440 hasRelatedWork W1583118900 @default.
- W2604927440 hasRelatedWork W1850357151 @default.
- W2604927440 hasRelatedWork W1983497902 @default.
- W2604927440 hasRelatedWork W2000379682 @default.
- W2604927440 hasRelatedWork W2029383230 @default.
- W2604927440 hasRelatedWork W2052789968 @default.
- W2604927440 hasRelatedWork W2103716188 @default.
- W2604927440 hasRelatedWork W2150916921 @default.
- W2604927440 hasRelatedWork W2578682410 @default.
- W2604927440 hasRelatedWork W2604965736 @default.
- W2604927440 hasRelatedWork W2615084866 @default.
- W2604927440 hasRelatedWork W2774102507 @default.
- W2604927440 hasRelatedWork W2909288660 @default.
- W2604927440 hasRelatedWork W2939552868 @default.
- W2604927440 hasRelatedWork W2943985748 @default.
- W2604927440 hasRelatedWork W2947120476 @default.
- W2604927440 hasRelatedWork W2966777221 @default.
- W2604927440 hasRelatedWork W3110419693 @default.
- W2604927440 hasRelatedWork W3123547349 @default.
- W2604927440 hasRelatedWork W3126684855 @default.
- W2604927440 isParatext "false" @default.
- W2604927440 isRetracted "false" @default.
- W2604927440 magId "2604927440" @default.
- W2604927440 workType "article" @default.