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- W2605002912 abstract "A 14-year-old girl presented with three months of increasing polydipsia and polyuria. Initial investigations revealed a blood glucose level of 28.4 mmol/L, pH 7.19 and large urine ketones. She was diagnosed with new-onset type 1 diabetes mellitus in diabetic ketoacidosis. She was started on subcutaneous insulin and showed clinical improvement.In the following days, her insulin requirement steadily increased. Ten days after diagnosis, she again presented to the emergency department with a six-day history of progressive swelling of her lower limbs, abdominal distention, joint pain and weakness. There was no history of shortness of breath, oliguria, jaundice or abdominal pain. Her weight had increased 10.2 kg since diagnosis. She had facial and sacral edema, and lower extremity pitting edema up to her calves. Her abdomen was distended with dullness to the flanks, and her liver edge was palpable 4 cm below the costal margin. Heart sounds were normal without S3, S4 or murmurs. Lung fields were clear, without crackles. Deep tendon reflexes were decreased and she had distal weakness. A chest x-ray showed no evidence of pleural effusion, and urinalysis showed no proteinuria. Further investigations and evaluation suggested the etiology of her presentation." @default.
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- W2605002912 date "2014-05-01" @default.
- W2605002912 modified "2023-09-26" @default.
- W2605002912 title "Case 2: Generalized swelling in a child with newly diagnosed diabetes mellitus" @default.
- W2605002912 cites W2015698112 @default.
- W2605002912 cites W4239404908 @default.
- W2605002912 doi "https://doi.org/10.1093/pch/19.5.233-b" @default.
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