FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2605280239> ?p ?o ?g. }

• W2605280239 endingPage "1431" @default.
• W2605280239 startingPage "1422" @default.
• W2605280239 abstract "Podoconiosis affects an estimated 3 million people in Ethiopia with a further 19 million at risk. Volcanic soil and pathogens enter skin breaches in the feet causing inflammation, lymphoedema and hyperkeratosis. There is no robust evidence on optimal podoconiosis skincare regimens to improve skin barrier function (SBF). To evaluate the effectiveness of a new, low‐cost, evidence‐based intervention to improve SBF in the lower limbs of those with podoconiosis. A randomized controlled trial (NCT02839772) was conducted over 3 months in two podoconiosis clinics (n = 193). The intervention comprised 2% (v/v) glycerine added to a reduced volume of soaking water. The control group received the current skincare regimen. Primary outcome measures were transepidermal water loss (TEWL) and stratum corneum hydration (SCH) at four specific sites on the lower limbs. Improvement in SBF was observed in both groups across all measurement sites and time points, although this was significantly greater in the experimental group. TEWL reduced in both groups at all sites. For example, on top of the foot the estimated group difference in TEWL at visit 4 was 1·751 [standard error (SE) = 0·0390] in favour of the experimental group [t = 3·15, degrees of freedom (df) = 189·58, P = 0·002, 95% confidence interval (CI) 0·066–2·85], indicating a greater reduction in TEWL in the experimental group. Similarly, at the same site the estimated group difference in SCH at visit 4 was −2·041 (SE = 0·572) in favour of the experimental group (t = −3·56, df = 186·74, P < 0·001, 95% CI −3·16 to −0·91), indicating a greater increase in SCH in the experimental group. There were also significantly greater reductions in odour, number of wounds and largest foot circumference in the experimental vs. the control group. The addition of 2% (v/v) glycerol to a reduced volume (83% reduction) of soaking water significantly improved SBF." @default.
• W2605280239 created "2017-04-14" @default.
• W2605280239 creator A5011938285 @default.
• W2605280239 creator A5034983733 @default.
• W2605280239 creator A5041774717 @default.
• W2605280239 creator A5044342160 @default.
• W2605280239 creator A5044469586 @default.
• W2605280239 creator A5050037785 @default.
• W2605280239 date "2017-11-01" @default.
• W2605280239 modified "2023-10-07" @default.
• W2605280239 title "A randomized controlled trial to evaluate the effect of a new skincare regimen on skin barrier function in those with podoconiosis in Ethiopia" @default.
• W2605280239 cites W1963552512 @default.
• W2605280239 cites W1971223238 @default.
• W2605280239 cites W2002706409 @default.
• W2605280239 cites W2023777632 @default.
• W2605280239 cites W2030518328 @default.
• W2605280239 cites W2043115617 @default.
• W2605280239 cites W2047882449 @default.
• W2605280239 cites W2048107051 @default.
• W2605280239 cites W2052339320 @default.
• W2605280239 cites W2069456037 @default.
• W2605280239 cites W2087792667 @default.
• W2605280239 cites W2100301990 @default.
• W2605280239 cites W2105810551 @default.
• W2605280239 cites W2106981272 @default.
• W2605280239 cites W2126225590 @default.
• W2605280239 cites W2143637830 @default.
• W2605280239 cites W2147057634 @default.
• W2605280239 cites W2522374423 @default.
• W2605280239 cites W2571779980 @default.
• W2605280239 doi "https://doi.org/10.1111/bjd.15543" @default.
• W2605280239 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28374907" @default.
• W2605280239 hasPublicationYear "2017" @default.
• W2605280239 type Work @default.
• W2605280239 sameAs 2605280239 @default.
• W2605280239 citedByCount "14" @default.
• W2605280239 countsByYear W26052802392017 @default.
• W2605280239 countsByYear W26052802392018 @default.
• W2605280239 countsByYear W26052802392019 @default.
• W2605280239 countsByYear W26052802392020 @default.
• W2605280239 countsByYear W26052802392021 @default.
• W2605280239 countsByYear W26052802392022 @default.
• W2605280239 countsByYear W26052802392023 @default.
• W2605280239 crossrefType "journal-article" @default.
• W2605280239 hasAuthorship W2605280239A5011938285 @default.
• W2605280239 hasAuthorship W2605280239A5034983733 @default.
• W2605280239 hasAuthorship W2605280239A5041774717 @default.
• W2605280239 hasAuthorship W2605280239A5044342160 @default.
• W2605280239 hasAuthorship W2605280239A5044469586 @default.
• W2605280239 hasAuthorship W2605280239A5050037785 @default.
• W2605280239 hasBestOaLocation W26052802392 @default.
• W2605280239 hasConcept C126322002 @default.
• W2605280239 hasConcept C141071460 @default.
• W2605280239 hasConcept C142724271 @default.
• W2605280239 hasConcept C16005928 @default.
• W2605280239 hasConcept C168563851 @default.
• W2605280239 hasConcept C2778370115 @default.
• W2605280239 hasConcept C2781413609 @default.
• W2605280239 hasConcept C44249647 @default.
• W2605280239 hasConcept C71924100 @default.
• W2605280239 hasConcept C95150158 @default.
• W2605280239 hasConceptScore W2605280239C126322002 @default.
• W2605280239 hasConceptScore W2605280239C141071460 @default.
• W2605280239 hasConceptScore W2605280239C142724271 @default.
• W2605280239 hasConceptScore W2605280239C16005928 @default.
• W2605280239 hasConceptScore W2605280239C168563851 @default.
• W2605280239 hasConceptScore W2605280239C2778370115 @default.
• W2605280239 hasConceptScore W2605280239C2781413609 @default.
• W2605280239 hasConceptScore W2605280239C44249647 @default.
• W2605280239 hasConceptScore W2605280239C71924100 @default.
• W2605280239 hasConceptScore W2605280239C95150158 @default.
• W2605280239 hasIssue "5" @default.
• W2605280239 hasLocation W26052802391 @default.
• W2605280239 hasLocation W26052802392 @default.
• W2605280239 hasLocation W26052802393 @default.
• W2605280239 hasLocation W26052802394 @default.
• W2605280239 hasLocation W26052802395 @default.
• W2605280239 hasLocation W26052802396 @default.
• W2605280239 hasLocation W26052802397 @default.
• W2605280239 hasOpenAccess W2605280239 @default.
• W2605280239 hasPrimaryLocation W26052802391 @default.
• W2605280239 hasRelatedWork W1586374228 @default.
• W2605280239 hasRelatedWork W2003938723 @default.
• W2605280239 hasRelatedWork W2047967234 @default.
• W2605280239 hasRelatedWork W2089201504 @default.
• W2605280239 hasRelatedWork W2118496982 @default.
• W2605280239 hasRelatedWork W2364998975 @default.
• W2605280239 hasRelatedWork W2369162477 @default.
• W2605280239 hasRelatedWork W2439875401 @default.
• W2605280239 hasRelatedWork W4238867864 @default.
• W2605280239 hasRelatedWork W2525756941 @default.
• W2605280239 hasVolume "177" @default.
• W2605280239 isParatext "false" @default.
• W2605280239 isRetracted "false" @default.
• W2605280239 magId "2605280239" @default.
• W2605280239 workType "article" @default.