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- W2605494213 abstract "Nontuberculous Mycobacteria are opportunist pathogens which have specific role in lymphadenitis, skin andrespiratory infections. Treatment of the disease due to these bacteria is difficult since these bacteria are resistant toa large scale of antibiotics. On the other hand, most kinds of these Mycobacteria cannot be identified, so they aremistreated under anti-tuberculosis cure. The aim of this research is to investigate the frequency of nontuberculousMycobacteria in patients suspected to tuberculosis in Golestan province, the most prevalent region of tuberculosisin Iran. This cross-sectional study was carried on 3336 patients suspected to tuberculosis referred to hospitals andhealth care centres in Golestan province during 2010-2011, 319 positive culture cases were collected. Identificationof species by using biochemical tests was done on the samples recognized as nontuberculous Mycobacteria; afterDNA extraction by boiling, 16S rRNA PCR was done and the species were identified by NCBI BLAST software.Among 319 culture positive samples, 16 (%5.01) cases were diagnosed as nontuberculous Mycobacteria and 3samples as Nocardia. Most of them were isolated from patients belonging to age groups 16-24 and older than 65years old. The most common species in this research were M.simiae (6 cases) and M. fortuitum (4 cases). Thefrequency of nontuberculous Mycobateria in our region (Golestan province) is less than other studied areas in Iran.Frequency of Mycobacterium simiae and M.fortuitum ,which are resistant to first line of anti-tuberculosis drugs,maybe one of the reasons of failure in the tuberculosis treatment in this province. Therefore, identification of speciesis necessary." @default.
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- W2605494213 date "2013-01-01" @default.
- W2605494213 modified "2023-09-24" @default.
- W2605494213 title "Non tuberculosis Mycobacteria isolated from tuberculosis patients in Golestanprovince, North of Iran" @default.
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