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- W2605511713 abstract "We investigated the effects of stress loading on the plasma levels of L-arginine using 13-week-old SHR and WKY rats. There was no significant difference in the L-arginine plasma levels in the resting groups of the SHR and WKY rats. A significant decrease in the L-arginine level was found in the SHR rats after stress loading. However, there was no change in L-arginine plasma levels between the stress group and the resting group of the WKY rats. Furthermore, we injected adrenaline or noradrenaline intraperitoneally to investigate the effects of catecholamines on the L-arginine plasma levels. Adrenaline, as well as noradrenaline, reduced the plasma levels of L-arginine in the SHR rats, whereas there was no significant change in the WKY rats. These findings indicate that there is an impairment of L-arginine metabolism in the SHR rats, and furthermore catecholamines such as adrenaline and noradrenaline play an important role in the change of plasma L-arginine levels after stress loading in the SHR rats." @default.
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- W2605511713 date "1992-01-01" @default.
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- W2605511713 title "Effect of Stress Loading on the Plasma L-arginine Level in SHR and WKY Rats" @default.
- W2605511713 doi "https://doi.org/10.5551/jat1973.20.12_1017" @default.
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