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- W2606284831 abstract "This paper reports on the kinetics of extraction of ketoconazole enantiomers in a Lewis cell, which accompanies by an inclusion reaction. The mass transfer model of the extraction process is established based on the homogeneous reaction mechanism and two-film theory. Factors such as stirring speed, phase contact area, and ketoconazole concentration are separately investigated. The obtained data show the inclusion reaction is a fast reaction. The reactions have been found to be first order for ketoconazole enantiomers and second order for hydroxypropyl-β-cyclodextrin with forward rate constants of 1.716 × 10−3 m6/(mol2·s) for (−)-ketoconazole and 2.067 × 10−3 m6/(mol2·s) for (+)-ketoconazole." @default.
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- W2606284831 date "2017-04-18" @default.
- W2606284831 modified "2023-09-27" @default.
- W2606284831 title "Study on the Extraction Kinetics of Ketoconazole with Hydroxypropyl-β-Cyclodextrin as a Selector" @default.
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- W2606284831 doi "https://doi.org/10.1002/kin.21088" @default.
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