FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2606370402> ?p ?o ?g. }

• W2606370402 endingPage "41020" @default.
• W2606370402 startingPage "41011" @default.
• W2606370402 abstract "Biomarkers that facilitate the prediction of disease recurrence in head and neck squamous cell carcinoma (HNSCC) may enable physicians to personalize treatment. In the current study, DNA promoter methylation of programmed cell death 1 (PDCD1, PD-1) was evaluated as a prognostic biomarker in HNSCC patients.High PDCD1 methylation (mPDCD1) was associated with a significantly shorter overall survival after surgical resection in both the discovery (HR = 2.24 [95%CI: 1.08-4.64], p = 0.029) and the validation cohort (HR = 1.54 [95%CI: 1.08-2.21], p = 0.017). In multivariate Cox proportional hazards analysis, PDCD1 methylation remained a significant prognostic factor for HNSCC (HR = 2.14 [95%CI: 1.19-3.84], p = 0.011). Further, mPDCD1 was strongly associated with the human papilloma virus (HPV) status.mPDCD1 was assessed retrospectively in a discovery cohort of 120 HNSCC patients treated at the University Hospital of Bonn and a validation cohort of 527 HNSCC cases analyzed by The Cancer Genome Atlas Research Network.PDCD1 methylation might aid the identification of HNSCC patients potentially benefitting from a radical or alternative treatment, particularly in the context of immunotherapies targeting PD-1/PD-L1." @default.
• W2606370402 created "2017-04-28" @default.
• W2606370402 creator A5000038661 @default.
• W2606370402 creator A5005719798 @default.
• W2606370402 creator A5012229709 @default.
• W2606370402 creator A5012714072 @default.
• W2606370402 creator A5017462100 @default.
• W2606370402 creator A5029722705 @default.
• W2606370402 creator A5033446747 @default.
• W2606370402 creator A5036274083 @default.
• W2606370402 creator A5041337624 @default.
• W2606370402 creator A5055932840 @default.
• W2606370402 creator A5056461046 @default.
• W2606370402 date "2017-04-21" @default.
• W2606370402 modified "2023-10-16" @default.
• W2606370402 title "<i>PDCD1</i> (<i>PD-1</i>) promoter methylation predicts outcome in head and neck squamous cell carcinoma patients" @default.
• W2606370402 cites W1761824857 @default.
• W2606370402 cites W1893566975 @default.
• W2606370402 cites W1980668617 @default.
• W2606370402 cites W1985182657 @default.
• W2606370402 cites W1990956554 @default.
• W2606370402 cites W2064302386 @default.
• W2606370402 cites W2065558544 @default.
• W2606370402 cites W2066671159 @default.
• W2606370402 cites W2071606440 @default.
• W2606370402 cites W2095844662 @default.
• W2606370402 cites W2098765233 @default.
• W2606370402 cites W2099764884 @default.
• W2606370402 cites W2110664940 @default.
• W2606370402 cites W2112278221 @default.
• W2606370402 cites W2123032740 @default.
• W2606370402 cites W2139376220 @default.
• W2606370402 cites W2141524808 @default.
• W2606370402 cites W2146906100 @default.
• W2606370402 cites W2149166037 @default.
• W2606370402 cites W2150474342 @default.
• W2606370402 cites W2152174367 @default.
• W2606370402 cites W2156304486 @default.
• W2606370402 cites W2166248474 @default.
• W2606370402 cites W2267121375 @default.
• W2606370402 cites W2287229942 @default.
• W2606370402 cites W2305033403 @default.
• W2606370402 cites W2340636398 @default.
• W2606370402 cites W2507880739 @default.
• W2606370402 cites W2508395664 @default.
• W2606370402 cites W2523194272 @default.
• W2606370402 cites W2553022605 @default.
• W2606370402 cites W2553733474 @default.
• W2606370402 cites W2560367415 @default.
• W2606370402 cites W2732229964 @default.
• W2606370402 cites W2811088815 @default.
• W2606370402 doi "https://doi.org/10.18632/oncotarget.17354" @default.
• W2606370402 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5522222" @default.
• W2606370402 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28487502" @default.
• W2606370402 hasPublicationYear "2017" @default.
• W2606370402 type Work @default.
• W2606370402 sameAs 2606370402 @default.
• W2606370402 citedByCount "38" @default.
• W2606370402 countsByYear W26063704022017 @default.
• W2606370402 countsByYear W26063704022018 @default.
• W2606370402 countsByYear W26063704022019 @default.
• W2606370402 countsByYear W26063704022020 @default.
• W2606370402 countsByYear W26063704022021 @default.
• W2606370402 countsByYear W26063704022022 @default.
• W2606370402 countsByYear W26063704022023 @default.
• W2606370402 crossrefType "journal-article" @default.
• W2606370402 hasAuthorship W2606370402A5000038661 @default.
• W2606370402 hasAuthorship W2606370402A5005719798 @default.
• W2606370402 hasAuthorship W2606370402A5012229709 @default.
• W2606370402 hasAuthorship W2606370402A5012714072 @default.
• W2606370402 hasAuthorship W2606370402A5017462100 @default.
• W2606370402 hasAuthorship W2606370402A5029722705 @default.
• W2606370402 hasAuthorship W2606370402A5033446747 @default.
• W2606370402 hasAuthorship W2606370402A5036274083 @default.
• W2606370402 hasAuthorship W2606370402A5041337624 @default.
• W2606370402 hasAuthorship W2606370402A5055932840 @default.
• W2606370402 hasAuthorship W2606370402A5056461046 @default.
• W2606370402 hasBestOaLocation W26063704021 @default.
• W2606370402 hasConcept C104317684 @default.
• W2606370402 hasConcept C121608353 @default.
• W2606370402 hasConcept C126322002 @default.
• W2606370402 hasConcept C143998085 @default.
• W2606370402 hasConcept C150194340 @default.
• W2606370402 hasConcept C151730666 @default.
• W2606370402 hasConcept C190727270 @default.
• W2606370402 hasConcept C2776530083 @default.
• W2606370402 hasConcept C2776833033 @default.
• W2606370402 hasConcept C2779343474 @default.
• W2606370402 hasConcept C2781197716 @default.
• W2606370402 hasConcept C502942594 @default.
• W2606370402 hasConcept C50382708 @default.
• W2606370402 hasConcept C55493867 @default.
• W2606370402 hasConcept C71924100 @default.
• W2606370402 hasConcept C72563966 @default.
• W2606370402 hasConcept C86803240 @default.
• W2606370402 hasConceptScore W2606370402C104317684 @default.
• W2606370402 hasConceptScore W2606370402C121608353 @default.
• W2606370402 hasConceptScore W2606370402C126322002 @default.

• next