FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2606502180> ?p ?o ?g. }

• W2606502180 endingPage "3394" @default.
• W2606502180 startingPage "3388" @default.
• W2606502180 abstract "Post-translational protein modification by ubiquitin (Ub) and Ub-like modifiers is orchestrated by the sequential action of Ub-activating, -conjugating, and -ligating enzymes to regulate a vast array of fundamental biological processes. Unsurprisingly, the dysregulation of the intricate interplay between ubiquitination and deubiquitination gives rise to numerous pathologies, most notably cancer and neurodegenerative diseases. While activity-based probes (ABPs) and assay reagents have been extensively developed and applied for deubiquitinating enzymes, similar tools for the Ub cascade have only recently emerged. Given the recent efforts to develop inhibitors for the Ub system, the urgency for developing ABPs and assay reagents is imminent. In this light, we comprehensively discuss the currently available ABPs with a focus on the newly developed reagents targeting the Ub cascade while illustrating their potential applications." @default.
• W2606502180 created "2017-04-28" @default.
• W2606502180 creator A5036817094 @default.
• W2606502180 creator A5055065367 @default.
• W2606502180 creator A5088622927 @default.
• W2606502180 date "2017-11-01" @default.
• W2606502180 modified "2023-10-09" @default.
• W2606502180 title "Advancing our Understanding of Ubiquitination Using the Ub-Toolkit" @default.
• W2606502180 cites W1794063461 @default.
• W2606502180 cites W1971190621 @default.
• W2606502180 cites W1976041483 @default.
• W2606502180 cites W1978135217 @default.
• W2606502180 cites W1988436650 @default.
• W2606502180 cites W1997952190 @default.
• W2606502180 cites W2001234769 @default.
• W2606502180 cites W2015560356 @default.
• W2606502180 cites W2030437460 @default.
• W2606502180 cites W2036468298 @default.
• W2606502180 cites W2058390840 @default.
• W2606502180 cites W2061252639 @default.
• W2606502180 cites W2062724943 @default.
• W2606502180 cites W2071483137 @default.
• W2606502180 cites W2073031564 @default.
• W2606502180 cites W2076194625 @default.
• W2606502180 cites W2085392012 @default.
• W2606502180 cites W2088724822 @default.
• W2606502180 cites W2099464495 @default.
• W2606502180 cites W2099598643 @default.
• W2606502180 cites W2110960544 @default.
• W2606502180 cites W2124324529 @default.
• W2606502180 cites W2135414262 @default.
• W2606502180 cites W2142794753 @default.
• W2606502180 cites W2143161083 @default.
• W2606502180 cites W2147917253 @default.
• W2606502180 cites W2149554987 @default.
• W2606502180 cites W2150731090 @default.
• W2606502180 cites W2155880545 @default.
• W2606502180 cites W2159000061 @default.
• W2606502180 cites W2167475134 @default.
• W2606502180 cites W2184335538 @default.
• W2606502180 cites W2290268596 @default.
• W2606502180 cites W2291388628 @default.
• W2606502180 cites W2310322011 @default.
• W2606502180 cites W2327328750 @default.
• W2606502180 cites W2328753773 @default.
• W2606502180 cites W2333020680 @default.
• W2606502180 cites W2334130133 @default.
• W2606502180 cites W2400558607 @default.
• W2606502180 cites W2400942913 @default.
• W2606502180 cites W2409179396 @default.
• W2606502180 cites W2430738920 @default.
• W2606502180 cites W2530082208 @default.
• W2606502180 cites W4213262935 @default.
• W2606502180 doi "https://doi.org/10.1016/j.jmb.2017.04.002" @default.
• W2606502180 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28410891" @default.
• W2606502180 hasPublicationYear "2017" @default.
• W2606502180 type Work @default.
• W2606502180 sameAs 2606502180 @default.
• W2606502180 citedByCount "18" @default.
• W2606502180 countsByYear W26065021802018 @default.
• W2606502180 countsByYear W26065021802019 @default.
• W2606502180 countsByYear W26065021802020 @default.
• W2606502180 countsByYear W26065021802021 @default.
• W2606502180 countsByYear W26065021802023 @default.
• W2606502180 crossrefType "journal-article" @default.
• W2606502180 hasAuthorship W2606502180A5036817094 @default.
• W2606502180 hasAuthorship W2606502180A5055065367 @default.
• W2606502180 hasAuthorship W2606502180A5088622927 @default.
• W2606502180 hasBestOaLocation W26065021801 @default.
• W2606502180 hasConcept C100631289 @default.
• W2606502180 hasConcept C102658986 @default.
• W2606502180 hasConcept C104317684 @default.
• W2606502180 hasConcept C181199279 @default.
• W2606502180 hasConcept C185592680 @default.
• W2606502180 hasConcept C25602115 @default.
• W2606502180 hasConcept C55493867 @default.
• W2606502180 hasConcept C70721500 @default.
• W2606502180 hasConcept C86803240 @default.
• W2606502180 hasConcept C95444343 @default.
• W2606502180 hasConceptScore W2606502180C100631289 @default.
• W2606502180 hasConceptScore W2606502180C102658986 @default.
• W2606502180 hasConceptScore W2606502180C104317684 @default.
• W2606502180 hasConceptScore W2606502180C181199279 @default.
• W2606502180 hasConceptScore W2606502180C185592680 @default.
• W2606502180 hasConceptScore W2606502180C25602115 @default.
• W2606502180 hasConceptScore W2606502180C55493867 @default.
• W2606502180 hasConceptScore W2606502180C70721500 @default.
• W2606502180 hasConceptScore W2606502180C86803240 @default.
• W2606502180 hasConceptScore W2606502180C95444343 @default.
• W2606502180 hasIssue "22" @default.
• W2606502180 hasLocation W26065021801 @default.
• W2606502180 hasLocation W26065021802 @default.
• W2606502180 hasLocation W26065021803 @default.
• W2606502180 hasOpenAccess W2606502180 @default.
• W2606502180 hasPrimaryLocation W26065021801 @default.
• W2606502180 hasRelatedWork W2020053069 @default.
• W2606502180 hasRelatedWork W2034032029 @default.
• W2606502180 hasRelatedWork W2056210416 @default.

• next