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- W2606543253 endingPage "832" @default.
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- W2606543253 abstract "Several conditions may alter the bone health in the oral cavity. These include a variety of bone fractures, tumors, infections, osteoporosis, and degenerative diseases, which may lead to bone loss, dental loosening, and development of large defects. Such defects should immediately be reconstructed by classic grafts. However, the auto- and allografts have significant limitations. Tissue-engineered based bone graft substitutes are the alternative option. In the recent years, nanomedicine has been developed and many nanostructures have been designed and synthesized to optimize the tissue-engineered based treatment strategies. These nanostructures vary based on the shape, structure, type of material, and several other factors. Nanoceramics, nanometals, and nanopolymers are the common nanomaterials used in bone healing. Different nanostructures, such as nanospheres, nanocrystals, and nanofibers have been used alone, or in combination with stem cells for numerous applications, such as increasing the scaffold bioactivity, controlling the infection and drug, gene and cell delivery. Although nanostructures may have value on bone health and repair, presence of some controversies and biases make the results difficult to conclude. This chapter covers the most important information regarding the manufacturing methods, available and future options, and the role of nanostructures on bone health, healing, and repair based on their basic to clinical evidences." @default.
- W2606543253 created "2017-04-28" @default.
- W2606543253 creator A5034720645 @default.
- W2606543253 creator A5042479677 @default.
- W2606543253 creator A5068730334 @default.
- W2606543253 creator A5081823744 @default.
- W2606543253 date "2017-01-01" @default.
- W2606543253 modified "2023-09-27" @default.
- W2606543253 title "The role of nanomedicine, nanotechnology, and nanostructures on oral bone healing, modeling, and remodeling" @default.
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