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• W2606662537 abstract "Parathyroid hormone (pth), parathyroid hormone-related peptide (pthrp) and their receptors are involved in the regulation of calcium homeostasis in all vertebrates. To further understand the role of these genes in teleosts during development, we investigated the expression pattern of pth1, pth2, pthrp1, pthrp2, and their receptors pth1r, pth2r, pth3r, and their response to acute salinity and temperature challenge during early development of zebrafish, Danio rerio. The results revealed that pth1, pth2, pthrp1, pthrp2, pth1r, pth2r, pth3r were differentially expressed during early development, and pth1, pthrp1, pth1r, pth2r mRNA were detected from 0 hpf. pth2 and pth3r mRNA were detected after fertilization. Exposure of zebrafish embryos and larvae to acute osmotic (30) stress for 15 min failed to modify the expression levels of pthrp2 mRNA from levels in control fish. However, salinity challenge significantly (P < 0.01) modified pth1, pth2, pth3r at 3 dpf, pthrp1 (P < 0.01) and pth1r (P < 0.05) were both significantly modified at 5 dpf, and pth2r was significantly (P < 0.01) modified at 4 dpf and 5 dpf. Exposure of embryos and larvae to a cold (18 °C) stress generally up-regulated mRNA levels of pth1, pth2, pthrp1, pthrp2 and pth3r from 2 dpf to 5 dpf, while a hot (38 °C) stress generally down-regulated mRNA levels of these genes. After acute temperature challenge, expression levels of pth receptors were greatly influenced except pth2r. The results indicate that the contribution of pth1, pth2, pthrp1, pthrp2, pth1r, pth2r and pth3r genes to the stress response in zebrafish may be stressor-specific during early development. Overall, the results from this study provide a basis for further research into the developmental and stressor-specific role of pth1, pth2, pthrp1, pthrp2, pth1r, pth2r and pth3r in zebrafish." @default.
• W2606662537 created "2017-04-28" @default.
• W2606662537 creator A5029908962 @default.
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• W2606662537 date "2017-03-01" @default.
• W2606662537 modified "2023-10-16" @default.
• W2606662537 title "Acute salinity and temperature challenges during early development of zebrafish: Differential gene expression of PTHs, PTHrPs and their receptors" @default.
• W2606662537 cites W1495437191 @default.
• W2606662537 cites W1527376733 @default.
• W2606662537 cites W1757679215 @default.
• W2606662537 cites W1964251185 @default.
• W2606662537 cites W1966446282 @default.
• W2606662537 cites W1978015907 @default.
• W2606662537 cites W1978726700 @default.
• W2606662537 cites W1980786859 @default.
• W2606662537 cites W1984381389 @default.
• W2606662537 cites W1986990049 @default.
• W2606662537 cites W1992993026 @default.
• W2606662537 cites W1993026913 @default.
• W2606662537 cites W1997074020 @default.
• W2606662537 cites W1999874570 @default.
• W2606662537 cites W1999906268 @default.
• W2606662537 cites W2005210647 @default.
• W2606662537 cites W2005344677 @default.
• W2606662537 cites W2005589757 @default.
• W2606662537 cites W2009955744 @default.
• W2606662537 cites W2012281687 @default.
• W2606662537 cites W2014096747 @default.
• W2606662537 cites W2017488052 @default.
• W2606662537 cites W2022954074 @default.
• W2606662537 cites W2025774390 @default.
• W2606662537 cites W2028681284 @default.
• W2606662537 cites W2033166635 @default.
• W2606662537 cites W2038261146 @default.
• W2606662537 cites W2041381837 @default.
• W2606662537 cites W2041669057 @default.
• W2606662537 cites W2042932723 @default.
• W2606662537 cites W2044785068 @default.
• W2606662537 cites W2044995747 @default.
• W2606662537 cites W2049943265 @default.
• W2606662537 cites W2059202479 @default.
• W2606662537 cites W2061013008 @default.
• W2606662537 cites W2064813976 @default.
• W2606662537 cites W2064912476 @default.
• W2606662537 cites W2067072664 @default.
• W2606662537 cites W2068720581 @default.
• W2606662537 cites W2069455469 @default.
• W2606662537 cites W2078344405 @default.
• W2606662537 cites W2082174769 @default.
• W2606662537 cites W2085756186 @default.
• W2606662537 cites W2092443658 @default.
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• W2606662537 cites W2094694331 @default.
• W2606662537 cites W2095893084 @default.
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• W2606662537 doi "https://doi.org/10.1016/j.aaf.2017.04.001" @default.
• W2606662537 hasPublicationYear "2017" @default.
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