FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2606800472> ?p ?o ?g. }

• W2606800472 abstract "Remission is arguably the ultimate therapeutic goal in rheumatoid arthritis (RA). Applying modern strategies, clinical remission can be achieved in a substantial number of patients with early RA (ERA). Even in those patients, the number and scope of erosions can increase. We, therefore, investigated the value of MRI for the detection of radiological progression in patients with DAS28 improvement and/or clinical remission of the German Remission-plus cohort. Data-sets of 80 RA patients (according to 2010 ACR/EULAR criteria) from the Remission-plus study cohort, who fulfilled the following criteria, were retrospectively analysed: availability of two consecutive MRI scans (low-field MRI, follow-up interval 1 year) of the clinically dominant hand and wrist, and the presence of DAS28 (CRP) scores at both time points, which was used to assess disease activity. Seventy-one of the 80 investigated patients presented a numerical improvement of the DAS28 (CRP) after 12 months (DAS28(CRP) T0 average (Ø) 4.96, SD 1.2; DAS28 T4 (12 month) Ø 2.6, SD 1.0), 73% of them also improved in the RAMRIS-Score, while 24% demonstrated an increase despite DAS28 improvement and 3% showed equal values. 48% of patients who improved in the DAS28 reached EULAR remission. 41% of these patients had an increase in the RAMRIS Erosion-subscore after 12 months. When considering EULAR response criteria (non-response (n = 7), moderate response (n = 19), good response (n = 45)), an increase of erosions was found in 71.4% of non-responders, 52.6% of moderate responders, and 31.1% of good responders after 12 months, all compared to baseline. Up to 40% of patients in this study demonstrated a progressive erosive disease detected by MRI despite DAS28 improvement or EULAR remission. Future studies are needed to determine the prognostic clinical impact of disease progression in MRI despite clinical remission, and to investigate if DAS28 remission may be an insufficient therapeutic goal and should be accompanied by MRI remission criteria." @default.
• W2606800472 created "2017-04-28" @default.
• W2606800472 creator A5001632492 @default.
• W2606800472 creator A5017675014 @default.
• W2606800472 creator A5019259943 @default.
• W2606800472 creator A5019710723 @default.
• W2606800472 creator A5022466144 @default.
• W2606800472 creator A5037134915 @default.
• W2606800472 creator A5042158209 @default.
• W2606800472 creator A5044796327 @default.
• W2606800472 creator A5056925919 @default.
• W2606800472 creator A5061090888 @default.
• W2606800472 date "2017-04-19" @default.
• W2606800472 modified "2023-10-18" @default.
• W2606800472 title "Silent progression in patients with rheumatoid arthritis: is DAS28 remission an insufficient goal in RA? Results from the German Remission-plus cohort" @default.
• W2606800472 cites W1440166142 @default.
• W2606800472 cites W1523575018 @default.
• W2606800472 cites W1790237971 @default.
• W2606800472 cites W1819049410 @default.
• W2606800472 cites W1969773816 @default.
• W2606800472 cites W1983134858 @default.
• W2606800472 cites W2000905503 @default.
• W2606800472 cites W2009274084 @default.
• W2606800472 cites W2012620405 @default.
• W2606800472 cites W2014283931 @default.
• W2606800472 cites W2022326743 @default.
• W2606800472 cites W2024209817 @default.
• W2606800472 cites W2055459141 @default.
• W2606800472 cites W2077013706 @default.
• W2606800472 cites W2099321660 @default.
• W2606800472 cites W2099680326 @default.
• W2606800472 cites W2103310388 @default.
• W2606800472 cites W2104669609 @default.
• W2606800472 cites W2110177517 @default.
• W2606800472 cites W2119074557 @default.
• W2606800472 cites W2136007246 @default.
• W2606800472 cites W2141830065 @default.
• W2606800472 cites W2146625574 @default.
• W2606800472 cites W2149586645 @default.
• W2606800472 cites W2152721826 @default.
• W2606800472 cites W2155109530 @default.
• W2606800472 cites W2159106700 @default.
• W2606800472 cites W2162351377 @default.
• W2606800472 cites W2164091576 @default.
• W2606800472 cites W2329049260 @default.
• W2606800472 cites W2336542538 @default.
• W2606800472 cites W4249063051 @default.
• W2606800472 doi "https://doi.org/10.1186/s12891-017-1528-y" @default.
• W2606800472 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5395882" @default.
• W2606800472 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28420375" @default.
• W2606800472 hasPublicationYear "2017" @default.
• W2606800472 type Work @default.
• W2606800472 sameAs 2606800472 @default.
• W2606800472 citedByCount "32" @default.
• W2606800472 countsByYear W26068004722018 @default.
• W2606800472 countsByYear W26068004722019 @default.
• W2606800472 countsByYear W26068004722020 @default.
• W2606800472 countsByYear W26068004722021 @default.
• W2606800472 countsByYear W26068004722022 @default.
• W2606800472 countsByYear W26068004722023 @default.
• W2606800472 crossrefType "journal-article" @default.
• W2606800472 hasAuthorship W2606800472A5001632492 @default.
• W2606800472 hasAuthorship W2606800472A5017675014 @default.
• W2606800472 hasAuthorship W2606800472A5019259943 @default.
• W2606800472 hasAuthorship W2606800472A5019710723 @default.
• W2606800472 hasAuthorship W2606800472A5022466144 @default.
• W2606800472 hasAuthorship W2606800472A5037134915 @default.
• W2606800472 hasAuthorship W2606800472A5042158209 @default.
• W2606800472 hasAuthorship W2606800472A5044796327 @default.
• W2606800472 hasAuthorship W2606800472A5056925919 @default.
• W2606800472 hasAuthorship W2606800472A5061090888 @default.
• W2606800472 hasBestOaLocation W26068004721 @default.
• W2606800472 hasConcept C126322002 @default.
• W2606800472 hasConcept C141071460 @default.
• W2606800472 hasConcept C198451711 @default.
• W2606800472 hasConcept C2777575956 @default.
• W2606800472 hasConcept C71924100 @default.
• W2606800472 hasConcept C72563966 @default.
• W2606800472 hasConceptScore W2606800472C126322002 @default.
• W2606800472 hasConceptScore W2606800472C141071460 @default.
• W2606800472 hasConceptScore W2606800472C198451711 @default.
• W2606800472 hasConceptScore W2606800472C2777575956 @default.
• W2606800472 hasConceptScore W2606800472C71924100 @default.
• W2606800472 hasConceptScore W2606800472C72563966 @default.
• W2606800472 hasIssue "1" @default.
• W2606800472 hasLocation W26068004721 @default.
• W2606800472 hasLocation W26068004722 @default.
• W2606800472 hasLocation W26068004723 @default.
• W2606800472 hasLocation W26068004724 @default.
• W2606800472 hasLocation W26068004725 @default.
• W2606800472 hasOpenAccess W2606800472 @default.
• W2606800472 hasPrimaryLocation W26068004721 @default.
• W2606800472 hasRelatedWork W2045151582 @default.
• W2606800472 hasRelatedWork W2082406232 @default.
• W2606800472 hasRelatedWork W2156283049 @default.
• W2606800472 hasRelatedWork W2316954211 @default.
• W2606800472 hasRelatedWork W2326094713 @default.
• W2606800472 hasRelatedWork W2427075784 @default.
• W2606800472 hasRelatedWork W2617939361 @default.
• W2606800472 hasRelatedWork W2761967325 @default.

• next