FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2606833132> ?p ?o ?g. }

• W2606833132 endingPage "1671" @default.
• W2606833132 startingPage "1659" @default.
• W2606833132 abstract "Cilia are cellular projections that assemble on centriole-derived basal bodies. While cilia assembly is absolutely dependent on centrioles, it is not known to what extent they contribute to downstream events. The nematode C. elegans provides a unique opportunity to address this question, as centrioles do not persist at the base of mature cilia. Using fluorescence microscopy and electron tomography, we find that centrioles degenerate early during ciliogenesis. The transition zone and axoneme are not completely formed at this time, indicating that cilia maturation does not depend on intact centrioles. The hydrolethalus syndrome protein HYLS-1 is the only centriolar protein known to remain at the base of mature cilia and is required for intraflagellar transport trafficking. Surprisingly, targeted degradation of HYLS-1 after initiation of ciliogenesis does not affect ciliary structures. Taken together, our results indicate that while centrioles are essential to initiate cilia formation, they are dispensable for cilia maturation and maintenance." @default.
• W2606833132 created "2017-04-28" @default.
• W2606833132 creator A5024214871 @default.
• W2606833132 creator A5036888835 @default.
• W2606833132 creator A5040502926 @default.
• W2606833132 creator A5074572864 @default.
• W2606833132 creator A5089085924 @default.
• W2606833132 date "2017-04-14" @default.
• W2606833132 modified "2023-10-05" @default.
• W2606833132 title "Centrioles initiate cilia assembly but are dispensable for maturation and maintenance in C. elegans" @default.
• W2606833132 cites W1899925323 @default.
• W2606833132 cites W1912876688 @default.
• W2606833132 cites W1962669878 @default.
• W2606833132 cites W1973153764 @default.
• W2606833132 cites W1973408837 @default.
• W2606833132 cites W1976311440 @default.
• W2606833132 cites W1977560942 @default.
• W2606833132 cites W1979826378 @default.
• W2606833132 cites W1980493259 @default.
• W2606833132 cites W1985225356 @default.
• W2606833132 cites W1985646870 @default.
• W2606833132 cites W1986997657 @default.
• W2606833132 cites W1989952069 @default.
• W2606833132 cites W1990195067 @default.
• W2606833132 cites W1990436838 @default.
• W2606833132 cites W2001204396 @default.
• W2606833132 cites W2005402136 @default.
• W2606833132 cites W2010025876 @default.
• W2606833132 cites W2012950009 @default.
• W2606833132 cites W2027771004 @default.
• W2606833132 cites W2029101220 @default.
• W2606833132 cites W2029852334 @default.
• W2606833132 cites W2030939638 @default.
• W2606833132 cites W2032513934 @default.
• W2606833132 cites W2033799985 @default.
• W2606833132 cites W2038678925 @default.
• W2606833132 cites W2041964741 @default.
• W2606833132 cites W2045900269 @default.
• W2606833132 cites W2049460100 @default.
• W2606833132 cites W2054219985 @default.
• W2606833132 cites W2057104531 @default.
• W2606833132 cites W2063293509 @default.
• W2606833132 cites W2066127197 @default.
• W2606833132 cites W2071209248 @default.
• W2606833132 cites W2073745454 @default.
• W2606833132 cites W2079458003 @default.
• W2606833132 cites W2085685974 @default.
• W2606833132 cites W2097126971 @default.
• W2606833132 cites W2098744495 @default.
• W2606833132 cites W2099247534 @default.
• W2606833132 cites W2102905759 @default.
• W2606833132 cites W2103390035 @default.
• W2606833132 cites W2110318878 @default.
• W2606833132 cites W2111952755 @default.
• W2606833132 cites W2121248205 @default.
• W2606833132 cites W2124406589 @default.
• W2606833132 cites W2125724672 @default.
• W2606833132 cites W2126879318 @default.
• W2606833132 cites W2127360608 @default.
• W2606833132 cites W2128508997 @default.
• W2606833132 cites W2135979384 @default.
• W2606833132 cites W2142161929 @default.
• W2606833132 cites W2145300367 @default.
• W2606833132 cites W2147083266 @default.
• W2606833132 cites W2151765044 @default.
• W2606833132 cites W2157443774 @default.
• W2606833132 cites W2159407840 @default.
• W2606833132 cites W2161659315 @default.
• W2606833132 cites W2161870393 @default.
• W2606833132 cites W2168056473 @default.
• W2606833132 cites W2177564588 @default.
• W2606833132 cites W2180541157 @default.
• W2606833132 cites W2188873428 @default.
• W2606833132 cites W2208957120 @default.
• W2606833132 cites W2277608960 @default.
• W2606833132 cites W2299076631 @default.
• W2606833132 cites W2409160347 @default.
• W2606833132 cites W2471599151 @default.
• W2606833132 cites W2515973749 @default.
• W2606833132 cites W2521166179 @default.
• W2606833132 cites W2951848036 @default.
• W2606833132 doi "https://doi.org/10.1083/jcb.201610070" @default.
• W2606833132 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5461022" @default.
• W2606833132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28411189" @default.
• W2606833132 hasPublicationYear "2017" @default.
• W2606833132 type Work @default.
• W2606833132 sameAs 2606833132 @default.
• W2606833132 citedByCount "48" @default.
• W2606833132 countsByYear W26068331322017 @default.
• W2606833132 countsByYear W26068331322018 @default.
• W2606833132 countsByYear W26068331322019 @default.
• W2606833132 countsByYear W26068331322020 @default.
• W2606833132 countsByYear W26068331322021 @default.
• W2606833132 countsByYear W26068331322022 @default.
• W2606833132 countsByYear W26068331322023 @default.
• W2606833132 crossrefType "journal-article" @default.
• W2606833132 hasAuthorship W2606833132A5024214871 @default.
• W2606833132 hasAuthorship W2606833132A5036888835 @default.

• next