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- W2606920422 startingPage "534" @default.
- W2606920422 abstract "Lactobacillus fermenti can utilize ornithine or citrulline, the same as arginine but the synthesis of arginine from ornithine or citrulline shows the lag phase in the initial period of culture. Pyridoxal is effective in shortening this lag phase. Canavanine inhibits the utilization of arginine and strongly inhibits utilization of ornithine or citrulline, i.e. biosynthesis of arginine. Arginine can recover growth inhibition at any concentration of canavanine, but such activity is weak in citrulline. The presence of canavanine in high concentrations makes it impossible to completely recover growth inhibition even by the increase of the amount of citrulline or by the extension of culture period. The antagonism between canavanine and arginine, and between canavanine and citrulline were found to be not competitive. In other words, the amount of canavanine against the unit concentration of citrulline when complete growth inhibition is indicated decreases extremely with the increase in the amount of citrulline. Canaline failed to inhibit the utilization of arginine, citrulline, or ornithine. Reaction center of canavanine was discussed briefly." @default.
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- W2606920422 date "1954-01-01" @default.
- W2606920422 modified "2023-09-27" @default.
- W2606920422 title "Studies on the Antimetabolites of Amino Acids. II" @default.
- W2606920422 doi "https://doi.org/10.1248/yakushi1947.74.5_534" @default.
- W2606920422 hasPublicationYear "1954" @default.
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