Matches in SemOpenAlex for { <https://semopenalex.org/work/W2606926532> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2606926532 endingPage "71" @default.
- W2606926532 startingPage "65" @default.
- W2606926532 abstract "There are clear guidelines and suggestions on the sample size and power calculation from health authorities (HA) for Bio equivalence (BE) studies in Healthy volunteers (HV). The suggested power is at least 80% and type 1 error is 5%. In real life situations, the clinical trials plan with more than 80%, giving rise to larger sample size. The increased power means more subjects, more wastage of time and more resources to complete the study, resulting in more money spent. This paper attempts to show how much reduction in the sample size can be achieved without affecting the scientific validity of the study and also the brief summary on the overall effect of reduced sample size on resources (subjects, time, blood and cost). We executed simulations in order to show the impact on the power and the 2 one sided confidence interval approach to show the study equivalence or otherwise. For illustration purpose, a couple of 2 period cross over studies were considered. 100 simulations were executed with different sample sizes to compare with the original results." @default.
- W2606926532 created "2017-04-28" @default.
- W2606926532 creator A5004755135 @default.
- W2606926532 creator A5083288832 @default.
- W2606926532 date "2017-04-07" @default.
- W2606926532 modified "2023-09-24" @default.
- W2606926532 title "Sample size recommendation for a bioequivalent study" @default.
- W2606926532 cites W1531013414 @default.
- W2606926532 cites W1533253850 @default.
- W2606926532 cites W1562127190 @default.
- W2606926532 cites W1577977464 @default.
- W2606926532 cites W1982660667 @default.
- W2606926532 cites W1988037948 @default.
- W2606926532 cites W1998678831 @default.
- W2606926532 cites W2006665787 @default.
- W2606926532 cites W2023731573 @default.
- W2606926532 cites W2029945961 @default.
- W2606926532 cites W2034631925 @default.
- W2606926532 cites W2040681657 @default.
- W2606926532 cites W2067047825 @default.
- W2606926532 cites W2072698696 @default.
- W2606926532 cites W2321997383 @default.
- W2606926532 cites W2474803679 @default.
- W2606926532 cites W2582743722 @default.
- W2606926532 cites W290345654 @default.
- W2606926532 cites W791627088 @default.
- W2606926532 doi "https://doi.org/10.6092/issn.1973-2201/6699" @default.
- W2606926532 hasPublicationYear "2017" @default.
- W2606926532 type Work @default.
- W2606926532 sameAs 2606926532 @default.
- W2606926532 citedByCount "0" @default.
- W2606926532 crossrefType "journal-article" @default.
- W2606926532 hasAuthorship W2606926532A5004755135 @default.
- W2606926532 hasAuthorship W2606926532A5083288832 @default.
- W2606926532 hasConcept C105795698 @default.
- W2606926532 hasConcept C112705442 @default.
- W2606926532 hasConcept C118615104 @default.
- W2606926532 hasConcept C126322002 @default.
- W2606926532 hasConcept C129848803 @default.
- W2606926532 hasConcept C149782125 @default.
- W2606926532 hasConcept C185592680 @default.
- W2606926532 hasConcept C198531522 @default.
- W2606926532 hasConcept C2780069185 @default.
- W2606926532 hasConcept C33923547 @default.
- W2606926532 hasConcept C40696583 @default.
- W2606926532 hasConcept C41008148 @default.
- W2606926532 hasConcept C42404028 @default.
- W2606926532 hasConcept C43617362 @default.
- W2606926532 hasConcept C44249647 @default.
- W2606926532 hasConcept C71924100 @default.
- W2606926532 hasConcept C96608239 @default.
- W2606926532 hasConceptScore W2606926532C105795698 @default.
- W2606926532 hasConceptScore W2606926532C112705442 @default.
- W2606926532 hasConceptScore W2606926532C118615104 @default.
- W2606926532 hasConceptScore W2606926532C126322002 @default.
- W2606926532 hasConceptScore W2606926532C129848803 @default.
- W2606926532 hasConceptScore W2606926532C149782125 @default.
- W2606926532 hasConceptScore W2606926532C185592680 @default.
- W2606926532 hasConceptScore W2606926532C198531522 @default.
- W2606926532 hasConceptScore W2606926532C2780069185 @default.
- W2606926532 hasConceptScore W2606926532C33923547 @default.
- W2606926532 hasConceptScore W2606926532C40696583 @default.
- W2606926532 hasConceptScore W2606926532C41008148 @default.
- W2606926532 hasConceptScore W2606926532C42404028 @default.
- W2606926532 hasConceptScore W2606926532C43617362 @default.
- W2606926532 hasConceptScore W2606926532C44249647 @default.
- W2606926532 hasConceptScore W2606926532C71924100 @default.
- W2606926532 hasConceptScore W2606926532C96608239 @default.
- W2606926532 hasIssue "1" @default.
- W2606926532 hasLocation W26069265321 @default.
- W2606926532 hasOpenAccess W2606926532 @default.
- W2606926532 hasPrimaryLocation W26069265321 @default.
- W2606926532 hasRelatedWork W1904671236 @default.
- W2606926532 hasRelatedWork W1983026544 @default.
- W2606926532 hasRelatedWork W1998278150 @default.
- W2606926532 hasRelatedWork W2003123700 @default.
- W2606926532 hasRelatedWork W2016243900 @default.
- W2606926532 hasRelatedWork W2021277102 @default.
- W2606926532 hasRelatedWork W2027210707 @default.
- W2606926532 hasRelatedWork W2032356149 @default.
- W2606926532 hasRelatedWork W2032918102 @default.
- W2606926532 hasRelatedWork W2048967367 @default.
- W2606926532 hasRelatedWork W2068588614 @default.
- W2606926532 hasRelatedWork W2072345061 @default.
- W2606926532 hasRelatedWork W2073812630 @default.
- W2606926532 hasRelatedWork W2103927790 @default.
- W2606926532 hasRelatedWork W2123845751 @default.
- W2606926532 hasRelatedWork W2259820912 @default.
- W2606926532 hasRelatedWork W2485032229 @default.
- W2606926532 hasRelatedWork W2792258657 @default.
- W2606926532 hasRelatedWork W3134636326 @default.
- W2606926532 hasRelatedWork W2044926778 @default.
- W2606926532 hasVolume "77" @default.
- W2606926532 isParatext "false" @default.
- W2606926532 isRetracted "false" @default.
- W2606926532 magId "2606926532" @default.
- W2606926532 workType "article" @default.