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- W2606926823 abstract "A highly enantioselective Friedel–Crafts arylation of indoles with isatins catalyzed by H8-1,1’-bi-2-naphthol (BINOL) imidodiphosphoric acids is reported here. This reaction proceeds smoothly under mild conditions and afford a range of 3-hydroxy-3-indolyloxindoles with high yields (<92 %) and excellent enantioselectivities (<99 % ee). To the best of our knowledge, this is the first example in which the highly enantioselective arylation of indoles with isatins has been catalyzed by a Brønsted acid." @default.
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- W2606926823 date "2017-05-29" @default.
- W2606926823 modified "2023-10-12" @default.
- W2606926823 title "Highly Enantioselective Friedel-Crafts Reactions of Indoles with Isatins Catalyzed by Chiral Imidodiphosphoric Acids" @default.
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- W2606926823 doi "https://doi.org/10.1002/ajoc.201700175" @default.
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