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- W2607091484 abstract "Abstract A rising awareness of natural products with hallucinogenic properties and their potential for abuse in recent years has led to the wider introduction of traditionally used medicines to the Western world. Among them are three plant extracts that present various medicinal properties. Extracts from Salvia divinorum (Diviner's sage), Mitragyna speciosa (Kratom), and Banisteriopsis caapi and Psychotria viridis (Ayahuasca) have gained interest both among public health and legal officials due to increased reports of their use for recreational purposes. There are confirmed active ingredients in each of these extracts that have been investigated further in vitro and in vivo as well as in human trials for both their potential medicinal benefits and their abuse potential. Salvinorin A from S. divinorum presents as a nonnitrogenous kappa opioid receptor agonist with potential applications for inflammation, pain, and depressive disorders. Mitragynine from M. speciosa has shown both opioid receptor and sympathomimetic activities and may provide applications in the treatment of pain and a variety of CNS disorders. N , N -Dimethyltryptamine from P. viridis , in combination with monoamine oxidase inhibitors from B. caapi , has long been useful in treating substance use disorders as well as depressive and anxiety afflictions. This chapter provides an overview of the mechanisms of action, structure-activity relationship, and current knowledge of the potential clinical applications of each extract and their respective active constituents and derivatives." @default.
- W2607091484 created "2017-04-28" @default.
- W2607091484 creator A5018396156 @default.
- W2607091484 creator A5045742344 @default.
- W2607091484 date "2017-01-01" @default.
- W2607091484 modified "2023-09-27" @default.
- W2607091484 title "Pharmacology and Structure-Activity Relationship of Natural Products With Psychoactive Effects From Salvia divinorum , Mitragyna speciosa , and Ayahuasca" @default.
- W2607091484 cites W104059927 @default.
- W2607091484 cites W1510556999 @default.
- W2607091484 cites W1534015176 @default.
- W2607091484 cites W1649318184 @default.
- W2607091484 cites W1719312516 @default.
- W2607091484 cites W1824548881 @default.
- W2607091484 cites W1844473199 @default.
- W2607091484 cites W1854968879 @default.
- W2607091484 cites W185824688 @default.
- W2607091484 cites W1872197089 @default.
- W2607091484 cites W1902779915 @default.
- W2607091484 cites W1960674406 @default.
- W2607091484 cites W1964814905 @default.
- W2607091484 cites W1964918564 @default.
- W2607091484 cites W1965689912 @default.
- W2607091484 cites W1967981270 @default.
- W2607091484 cites W1971304937 @default.
- W2607091484 cites W1972968028 @default.
- W2607091484 cites W1975784887 @default.
- W2607091484 cites W1976480594 @default.
- W2607091484 cites W1981073133 @default.
- W2607091484 cites W1982063200 @default.
- W2607091484 cites W1987616048 @default.
- W2607091484 cites W1988743423 @default.
- W2607091484 cites W1988815794 @default.
- W2607091484 cites W1989476589 @default.
- W2607091484 cites W1992914052 @default.
- W2607091484 cites W1993599005 @default.
- W2607091484 cites W1994146471 @default.
- W2607091484 cites W1996161840 @default.
- W2607091484 cites W1997127782 @default.
- W2607091484 cites W1998274145 @default.
- W2607091484 cites W1999094536 @default.
- W2607091484 cites W2002330441 @default.
- W2607091484 cites W2002549690 @default.
- W2607091484 cites W2003119283 @default.
- W2607091484 cites W2004109806 @default.
- W2607091484 cites W2004476604 @default.
- W2607091484 cites W2005643237 @default.
- W2607091484 cites W2005997645 @default.
- W2607091484 cites W2012159028 @default.
- W2607091484 cites W2012413090 @default.
- W2607091484 cites W2014596337 @default.
- W2607091484 cites W2015332250 @default.
- W2607091484 cites W2015778368 @default.
- W2607091484 cites W201702608 @default.
- W2607091484 cites W2018132456 @default.
- W2607091484 cites W2018910518 @default.
- W2607091484 cites W2018957682 @default.
- W2607091484 cites W2022115750 @default.
- W2607091484 cites W2023033984 @default.
- W2607091484 cites W2023565656 @default.
- W2607091484 cites W2025750773 @default.
- W2607091484 cites W2026582490 @default.
- W2607091484 cites W2027389347 @default.
- W2607091484 cites W2028839532 @default.
- W2607091484 cites W2029197384 @default.
- W2607091484 cites W2030252531 @default.
- W2607091484 cites W2033675236 @default.
- W2607091484 cites W2034894507 @default.
- W2607091484 cites W2039250772 @default.
- W2607091484 cites W2042569825 @default.
- W2607091484 cites W2044412002 @default.
- W2607091484 cites W2045135727 @default.
- W2607091484 cites W2047050449 @default.
- W2607091484 cites W2047969260 @default.
- W2607091484 cites W2051579023 @default.
- W2607091484 cites W2054387861 @default.
- W2607091484 cites W2055682898 @default.
- W2607091484 cites W2058526773 @default.
- W2607091484 cites W2061940435 @default.
- W2607091484 cites W2062339243 @default.
- W2607091484 cites W2063645761 @default.
- W2607091484 cites W2066423907 @default.
- W2607091484 cites W2074731904 @default.
- W2607091484 cites W2075327232 @default.
- W2607091484 cites W2085670677 @default.
- W2607091484 cites W2086889919 @default.
- W2607091484 cites W2086961054 @default.
- W2607091484 cites W2088721778 @default.
- W2607091484 cites W2089598859 @default.
- W2607091484 cites W2092304168 @default.
- W2607091484 cites W2095447303 @default.
- W2607091484 cites W2098079718 @default.
- W2607091484 cites W2100834566 @default.
- W2607091484 cites W2101808966 @default.
- W2607091484 cites W2103583518 @default.
- W2607091484 cites W2106410954 @default.
- W2607091484 cites W2106933585 @default.
- W2607091484 cites W2107376791 @default.
- W2607091484 cites W2108337682 @default.
- W2607091484 cites W2108609891 @default.
- W2607091484 cites W2109064856 @default.