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- W2607114311 abstract "Four prenylated flavonoids compounds 1-4, named sinopodophyllines A-D, and a flavonoid glycoside (compound 13), sinopodophylliside A, together with 19 known compounds (compounds 5-12 and 14-24) were isolated from the fruits of Sinopodophyllum hexandrum. The structures of new compounds were elucidated by extensive spectroscopic analysis, including HRESIMS, 1D and 2D NMR. Compounds 1-6, 9-11, and 14-17 were tested for their cytotoxicity against human breast-cancer T47D, MCF-7 and MDA-MB-231 cells in vitro, and compounds 2, 5, 6, 10 and 11 showed significant cytotoxicity (IC50 values < 10 μmol·L-1) against T47D cells." @default.
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- W2607114311 date "2017-03-01" @default.
- W2607114311 modified "2023-09-26" @default.
- W2607114311 title "Flavonoids isolated from Sinopodophylli Fructus and their bioactivities against human breast cancer cells" @default.
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- W2607114311 doi "https://doi.org/10.1016/s1875-5364(17)30039-0" @default.
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