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- W2607222572 abstract "The resistance among various opportunistic Fusarium species to different antifungal agents has emerged as a cause of public health problems worldwide. Considering the significance of multi-drug resistant (MDR), this paper emphasizes the problems associated with MDR and the need to understand its clinical significance to combat microbial infections. The search platform PubMed/MEDLINE and a review of 32 cases revealed a common multidrug-resistant profile exists, and clinically relevant members of Fusarium are intrinsically resistant to most currently used antifungals. Dissemination occurs in patients with prolonged neutropenia, immune deficiency, and especially hematological malignancies. Amphotericin B displayed the lowest minimum inhibitory concentrarions (MICs) followed by voriconazole, and posaconazole. Itraconazole and fluconazole showed high MIC values, displaying in vitro resistance. Echinocandins showed the highest MIC values. Seven out of ten (70%) patients with neutropenia died, including those with fungemia that progressed to skin lesions. Clinical Fusarium isolates displayed a common MDR profile and high MIC values for the most available antifungal agents with species- and strain-specific differences in antifungal susceptibility. Species identification of Fusarium infections is important. While the use of natamycin resulted in a favorable outcome in keratitis, AmB and VRC are the most used agents for the treatment of fusariosis in clinical settings." @default.
- W2607222572 created "2017-04-28" @default.
- W2607222572 creator A5081260790 @default.
- W2607222572 date "2017-04-10" @default.
- W2607222572 modified "2023-10-18" @default.
- W2607222572 title "Reduced Multidrug Susceptibility Profile Is a Common Feature of Opportunistic Fusarium Species: Fusarium Multi-Drug Resistant Pattern" @default.
- W2607222572 cites W1533112018 @default.
- W2607222572 cites W1790707390 @default.
- W2607222572 cites W1823771015 @default.
- W2607222572 cites W1893972893 @default.
- W2607222572 cites W1948212761 @default.
- W2607222572 cites W1958739631 @default.
- W2607222572 cites W1963920406 @default.
- W2607222572 cites W1966027330 @default.
- W2607222572 cites W1966199662 @default.
- W2607222572 cites W1967749841 @default.
- W2607222572 cites W1970865521 @default.
- W2607222572 cites W1973377550 @default.
- W2607222572 cites W1973926167 @default.
- W2607222572 cites W1984409867 @default.
- W2607222572 cites W1986835141 @default.
- W2607222572 cites W1987557285 @default.
- W2607222572 cites W1995763500 @default.
- W2607222572 cites W1998209502 @default.
- W2607222572 cites W2004832513 @default.
- W2607222572 cites W2007554671 @default.
- W2607222572 cites W2010185974 @default.
- W2607222572 cites W2010701746 @default.
- W2607222572 cites W2015015883 @default.
- W2607222572 cites W2017392894 @default.
- W2607222572 cites W2019276485 @default.
- W2607222572 cites W2046331374 @default.
- W2607222572 cites W2054977353 @default.
- W2607222572 cites W2060343335 @default.
- W2607222572 cites W2061492510 @default.
- W2607222572 cites W2061777873 @default.
- W2607222572 cites W2063094661 @default.
- W2607222572 cites W2067556492 @default.
- W2607222572 cites W2068449255 @default.
- W2607222572 cites W2068814532 @default.
- W2607222572 cites W2069975257 @default.
- W2607222572 cites W2071738328 @default.
- W2607222572 cites W2073369629 @default.
- W2607222572 cites W2074421272 @default.
- W2607222572 cites W2074680270 @default.
- W2607222572 cites W2075767753 @default.
- W2607222572 cites W2078268056 @default.
- W2607222572 cites W2080799591 @default.
- W2607222572 cites W2086641201 @default.
- W2607222572 cites W2099295686 @default.
- W2607222572 cites W2099427890 @default.
- W2607222572 cites W2104920773 @default.
- W2607222572 cites W2105125514 @default.
- W2607222572 cites W2107794472 @default.
- W2607222572 cites W2110040696 @default.
- W2607222572 cites W2114202103 @default.
- W2607222572 cites W2116582646 @default.
- W2607222572 cites W2118261118 @default.
- W2607222572 cites W2121541400 @default.
- W2607222572 cites W2121711759 @default.
- W2607222572 cites W2121868121 @default.
- W2607222572 cites W2129227816 @default.
- W2607222572 cites W2131462267 @default.
- W2607222572 cites W2132758664 @default.
- W2607222572 cites W2142652326 @default.
- W2607222572 cites W2143418842 @default.
- W2607222572 cites W2145564738 @default.
- W2607222572 cites W2147224863 @default.
- W2607222572 cites W2149960439 @default.
- W2607222572 cites W2154522347 @default.
- W2607222572 cites W2155745714 @default.
- W2607222572 cites W2166734004 @default.
- W2607222572 cites W2166960549 @default.
- W2607222572 cites W2170305176 @default.
- W2607222572 cites W2255539393 @default.
- W2607222572 cites W2312180805 @default.
- W2607222572 cites W2315602834 @default.
- W2607222572 cites W2317368723 @default.
- W2607222572 cites W2330596174 @default.
- W2607222572 cites W2335136657 @default.
- W2607222572 cites W2339582982 @default.
- W2607222572 cites W2345506121 @default.
- W2607222572 cites W2349539459 @default.
- W2607222572 cites W2411775298 @default.
- W2607222572 cites W2434164772 @default.
- W2607222572 cites W2467290617 @default.
- W2607222572 cites W2473101150 @default.
- W2607222572 cites W2474018472 @default.
- W2607222572 cites W2481695400 @default.
- W2607222572 cites W2511039966 @default.
- W2607222572 cites W2530046585 @default.
- W2607222572 cites W2560360976 @default.
- W2607222572 cites W2560830945 @default.
- W2607222572 cites W4378652493 @default.
- W2607222572 cites W602228121 @default.
- W2607222572 cites W137129318 @default.
- W2607222572 doi "https://doi.org/10.3390/jof3020018" @default.
- W2607222572 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5715927" @default.