FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2607265482> ?p ?o ?g. }

• W2607265482 endingPage "131" @default.
• W2607265482 startingPage "125" @default.
• W2607265482 abstract "Acacia cochliacantha is a small tree whose foliage is traditionally used in Mexico for treatment of kidney pain, gastrointestinal illnesses and to kill intestinal parasites. In recent decades, the study of vegetal extracts has offered other possible alternatives for the control of Haemonchus contortus. Considering that this nematode affects dramatically the health and productivity of small ruminants, the aim of this study was to identify the anthelmintic compounds from A. cochliacantha hydro-alcoholic extract (HA-E) through an ovicidal test.In vitro egg hatch assay was conducted to determinate the anthelmintic effects of a HA-E (60g). Liquid-liquid ethyl acetate/water extraction gave two fractions (EtOAc-F, 1.92g; Aq-F; 58.1g). The less polar compounds from ethyl acetate fraction were extracted by addition of dichloromethane offering a precipitate phase (Mt-F, 1.25g) and a soluble mixture (DCMt-F 1.15g). All fractions were evaluated for ovicidal activity obtaining the egg hatching inhibition (EHI, 0.07-25mg/mL). Ivermectin (0.5mg/mL) was used as a reference drug (positive control), and distilled water, 2.5% DMSO and 2% methanol were used as negative controls. The isolated compounds from the most active fractions were subjected to spectroscopic (1H NMR) Spectrometric (MS) and UV HPLC analysis in order to identify the bioactive compounds.The less polar treatments (AcOEt-F, DCMt-F, DCMt-P) showed the highest ovicidal activities (98-100% EHI; at 0.62-1.56mg/mL) and the major compounds found in these fractions were identified as caffeoyl and coumaroyl derivatives, including caffeic acid (1), p-coumaric acid (2), ferulic acid (3), methyl caffeate (4), methyl-p-coumarate (5), methyl ferulate (6) and quercetin. In case of the less active fractions (Aq-F, Mt-F) were constituted principally by glycosylated flavonoids.These results show that caffeoyl and coumaroyl derivatives from Acacia cochliacantha leaves had promising anthelmintic activity against Haemonchus contortus. This leguminous may offer an alternative source for the control of gastrointestinal nematodes of small ruminants." @default.
• W2607265482 created "2017-04-28" @default.
• W2607265482 creator A5018363006 @default.
• W2607265482 creator A5030735953 @default.
• W2607265482 creator A5032807845 @default.
• W2607265482 creator A5034510492 @default.
• W2607265482 creator A5047265782 @default.
• W2607265482 creator A5055738847 @default.
• W2607265482 creator A5078150213 @default.
• W2607265482 creator A5079221989 @default.
• W2607265482 creator A5081333307 @default.
• W2607265482 creator A5086415109 @default.
• W2607265482 creator A5088840267 @default.
• W2607265482 date "2017-05-01" @default.
• W2607265482 modified "2023-10-17" @default.
• W2607265482 title "Caffeoyl and coumaroyl derivatives from Acacia cochliacantha exhibit ovicidal activity against Haemonchus contortus" @default.
• W2607265482 cites W1559885054 @default.
• W2607265482 cites W1772977798 @default.
• W2607265482 cites W1786509730 @default.
• W2607265482 cites W1966778226 @default.
• W2607265482 cites W1981047789 @default.
• W2607265482 cites W1988924022 @default.
• W2607265482 cites W1997989710 @default.
• W2607265482 cites W2002578462 @default.
• W2607265482 cites W2006826353 @default.
• W2607265482 cites W2016235597 @default.
• W2607265482 cites W2041327979 @default.
• W2607265482 cites W2045614330 @default.
• W2607265482 cites W2047866622 @default.
• W2607265482 cites W2051798652 @default.
• W2607265482 cites W2084155778 @default.
• W2607265482 cites W2123245708 @default.
• W2607265482 cites W2136182960 @default.
• W2607265482 cites W2148028223 @default.
• W2607265482 cites W2151133681 @default.
• W2607265482 cites W2304481239 @default.
• W2607265482 cites W2410982588 @default.
• W2607265482 cites W2519399772 @default.
• W2607265482 cites W2520231503 @default.
• W2607265482 cites W2528640275 @default.
• W2607265482 cites W2560386621 @default.
• W2607265482 cites W30888072 @default.
• W2607265482 cites W4246253563 @default.
• W2607265482 doi "https://doi.org/10.1016/j.jep.2017.04.010" @default.
• W2607265482 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28414046" @default.
• W2607265482 hasPublicationYear "2017" @default.
• W2607265482 type Work @default.
• W2607265482 sameAs 2607265482 @default.
• W2607265482 citedByCount "38" @default.
• W2607265482 countsByYear W26072654822017 @default.
• W2607265482 countsByYear W26072654822018 @default.
• W2607265482 countsByYear W26072654822019 @default.
• W2607265482 countsByYear W26072654822020 @default.
• W2607265482 countsByYear W26072654822021 @default.
• W2607265482 countsByYear W26072654822022 @default.
• W2607265482 countsByYear W26072654822023 @default.
• W2607265482 crossrefType "journal-article" @default.
• W2607265482 hasAuthorship W2607265482A5018363006 @default.
• W2607265482 hasAuthorship W2607265482A5030735953 @default.
• W2607265482 hasAuthorship W2607265482A5032807845 @default.
• W2607265482 hasAuthorship W2607265482A5034510492 @default.
• W2607265482 hasAuthorship W2607265482A5047265782 @default.
• W2607265482 hasAuthorship W2607265482A5055738847 @default.
• W2607265482 hasAuthorship W2607265482A5078150213 @default.
• W2607265482 hasAuthorship W2607265482A5079221989 @default.
• W2607265482 hasAuthorship W2607265482A5081333307 @default.
• W2607265482 hasAuthorship W2607265482A5086415109 @default.
• W2607265482 hasAuthorship W2607265482A5088840267 @default.
• W2607265482 hasConcept C185592680 @default.
• W2607265482 hasConcept C18903297 @default.
• W2607265482 hasConcept C2776908094 @default.
• W2607265482 hasConcept C2778830712 @default.
• W2607265482 hasConcept C2779429693 @default.
• W2607265482 hasConcept C2779825395 @default.
• W2607265482 hasConcept C2779858419 @default.
• W2607265482 hasConcept C2780400988 @default.
• W2607265482 hasConcept C2780471494 @default.
• W2607265482 hasConcept C43617362 @default.
• W2607265482 hasConcept C55493867 @default.
• W2607265482 hasConcept C556039675 @default.
• W2607265482 hasConcept C71924100 @default.
• W2607265482 hasConcept C86803240 @default.
• W2607265482 hasConceptScore W2607265482C185592680 @default.
• W2607265482 hasConceptScore W2607265482C18903297 @default.
• W2607265482 hasConceptScore W2607265482C2776908094 @default.
• W2607265482 hasConceptScore W2607265482C2778830712 @default.
• W2607265482 hasConceptScore W2607265482C2779429693 @default.
• W2607265482 hasConceptScore W2607265482C2779825395 @default.
• W2607265482 hasConceptScore W2607265482C2779858419 @default.
• W2607265482 hasConceptScore W2607265482C2780400988 @default.
• W2607265482 hasConceptScore W2607265482C2780471494 @default.
• W2607265482 hasConceptScore W2607265482C43617362 @default.
• W2607265482 hasConceptScore W2607265482C55493867 @default.
• W2607265482 hasConceptScore W2607265482C556039675 @default.
• W2607265482 hasConceptScore W2607265482C71924100 @default.
• W2607265482 hasConceptScore W2607265482C86803240 @default.
• W2607265482 hasLocation W26072654821 @default.
• W2607265482 hasLocation W26072654822 @default.

• next