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• W2607434534 abstract "Significance Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with wide clinical variability and a complex pathogenesis. One of the hallmarks of ALS is the presence of diverse inclusions formed by apparently disparate misfolded proteins, which are unrelated in sequence, structure, function, and localization. Many of these proteins, in addition, are not the usual interaction partners of the primary inclusion-forming ALS-related proteins (SOD1, TDP-43, and FUS). Here, we show that a common feature of these coaggregating proteins is their metastability to aggregation in spinal motor neurons. These results suggest that as protein homeostasis becomes progressively impaired in ALS, supersaturated proteins in an ALS-specific group fail to be maintained in their soluble states, leading to their presence in ALS-associated inclusions." @default.
• W2607434534 created "2017-04-28" @default.
• W2607434534 creator A5004866198 @default.
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• W2607434534 creator A5067931683 @default.
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• W2607434534 creator A5075883279 @default.
• W2607434534 creator A5086564739 @default.
• W2607434534 creator A5091898546 @default.
• W2607434534 date "2017-04-10" @default.
• W2607434534 modified "2023-10-10" @default.
• W2607434534 title "Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS" @default.
• W2607434534 cites W1143895086 @default.
• W2607434534 cites W1487455238 @default.
• W2607434534 cites W1546589453 @default.
• W2607434534 cites W1619082318 @default.
• W2607434534 cites W1966202673 @default.
• W2607434534 cites W1967025628 @default.
• W2607434534 cites W1970577444 @default.
• W2607434534 cites W1974448552 @default.
• W2607434534 cites W1981160857 @default.
• W2607434534 cites W1982255500 @default.
• W2607434534 cites W1982708642 @default.
• W2607434534 cites W1983633543 @default.
• W2607434534 cites W1986369698 @default.
• W2607434534 cites W1990145006 @default.
• W2607434534 cites W1992002234 @default.
• W2607434534 cites W2008980964 @default.
• W2607434534 cites W2010089695 @default.
• W2607434534 cites W2013346318 @default.
• W2607434534 cites W2017286242 @default.
• W2607434534 cites W2020159880 @default.
• W2607434534 cites W2022814422 @default.
• W2607434534 cites W2023556666 @default.
• W2607434534 cites W2025851491 @default.
• W2607434534 cites W2027456357 @default.
• W2607434534 cites W2028746054 @default.
• W2607434534 cites W2029445248 @default.
• W2607434534 cites W2031964319 @default.
• W2607434534 cites W2032429337 @default.
• W2607434534 cites W2032670789 @default.
• W2607434534 cites W2040621074 @default.
• W2607434534 cites W2044246569 @default.
• W2607434534 cites W2048813950 @default.
• W2607434534 cites W2051349181 @default.
• W2607434534 cites W2052143537 @default.
• W2607434534 cites W2052888134 @default.
• W2607434534 cites W2056499061 @default.
• W2607434534 cites W2067015275 @default.
• W2607434534 cites W2069537999 @default.
• W2607434534 cites W2072981065 @default.
• W2607434534 cites W2073073462 @default.
• W2607434534 cites W2074726646 @default.
• W2607434534 cites W2076159058 @default.
• W2607434534 cites W2076788657 @default.
• W2607434534 cites W2081362575 @default.
• W2607434534 cites W2081457844 @default.
• W2607434534 cites W2082382374 @default.
• W2607434534 cites W2092751120 @default.
• W2607434534 cites W2096386031 @default.
• W2607434534 cites W2096891550 @default.
• W2607434534 cites W2101687573 @default.
• W2607434534 cites W2105028572 @default.
• W2607434534 cites W2110551795 @default.
• W2607434534 cites W2112552649 @default.
• W2607434534 cites W2117279697 @default.
• W2607434534 cites W2123939448 @default.
• W2607434534 cites W2127861463 @default.
• W2607434534 cites W2128815118 @default.
• W2607434534 cites W2129150800 @default.
• W2607434534 cites W2130565053 @default.
• W2607434534 cites W2130741221 @default.
• W2607434534 cites W2133408527 @default.
• W2607434534 cites W2134439639 @default.
• W2607434534 cites W2135607950 @default.
• W2607434534 cites W2135845674 @default.
• W2607434534 cites W2136305293 @default.
• W2607434534 cites W2138852996 @default.
• W2607434534 cites W2146554687 @default.
• W2607434534 cites W2154945114 @default.
• W2607434534 cites W2156236044 @default.
• W2607434534 cites W2159482845 @default.
• W2607434534 cites W2162928171 @default.
• W2607434534 cites W2163058306 @default.
• W2607434534 cites W2163289722 @default.
• W2607434534 cites W2164435689 @default.
• W2607434534 cites W2164683872 @default.
• W2607434534 cites W2164918307 @default.
• W2607434534 cites W2165186407 @default.
• W2607434534 cites W2167113152 @default.
• W2607434534 cites W2272042925 @default.
• W2607434534 cites W2340895726 @default.
• W2607434534 cites W2341194710 @default.
• W2607434534 cites W2481253841 @default.

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