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- W2607671640 abstract "Obesity is associated with an increased risk of infection. Unfortunately clinical trials examining the safety and efficacy of antibiotics in obese patients are deficient. Thus, clinicians predominately rely on pharmacokinetic and pharmacodynamic data for appropriate antibiotic dosing. The current literature for vancomycin, aminoglycosides, beta-lactams, fluoroquinolones, linezolid, and macrolides was reviewed to evaluate appropriate dosing in obese patients. Due to the limited number of studies and various pharmacokinetic parameters of antibiotics, dosing should be based on both patient- and drug-specific factors." @default.
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- W2607671640 date "2013-07-04" @default.
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- W2607671640 title "Underdosing in obesity—an epidemic: Focus on antibiotics" @default.
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