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- W2607852538 abstract "The first total synthesis of (±)-EA-2801, a naturally occurring 4-hydroxycyclopent-2-en-1-one acrylate produced by the fungus Trichoderma atroviridae UB-LMA, was achieved The synthesis started from furfuryl alcohol, manufactured industrially from furfural, produced from waste biomass such as corncobs or sugar cane bagasse. (±)-EA-2801 was synthesized in 5 steps and 71% overall yield starting from 4-hydroxycyclopent-2-en-1-one. Enantio-pure (R)- and (S)-EA-2801 were obtained from racemic mixture by preparative chiral supercritical fluid chromatography (SFC)." @default.
- W2607852538 created "2017-05-05" @default.
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- W2607852538 date "2017-06-01" @default.
- W2607852538 modified "2023-10-18" @default.
- W2607852538 title "Total synthesis of the antibiotic 4-hydroxycyclopent-2-en-1-one acrylate derivative EA-2801" @default.
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- W2607852538 doi "https://doi.org/10.1016/j.tetlet.2017.04.086" @default.
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