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- W2607886544 abstract "ABSTRACT Introduction This study's objective was to evaluate quantitative electromyography (QEMG) using multiple‐motor‐unit (multi‐MUP) analysis in Duchenne muscular dystrophy (DMD). Methods Ambulatory DMD boys, aged 5–15 years, were evaluated with QEMG at 6‐month intervals over 14 months. EMG was performed in the right biceps brachii (BB) and tibialis anterior (TA) muscles. Normative QEMG data were obtained from age‐matched healthy boys. Wilcoxon signed‐rank tests were performed. Results Eighteen DMD subjects were enrolled, with a median age of 7 (interquartile range 7–10) years. Six‐month evaluations were performed on 14 subjects. QEMG showed significantly abnormal mean MUP duration in BB and TA muscles, with no significant change over 6 months. Conclusions QEMG is a sensitive electrophysiological marker of myopathy in DMD. Preliminary data do not reflect a significant change in MUP parameters over a 6‐month interval; long‐term follow‐up QEMG studies are needed to understand its role as a biomarker for disease progression. Muscle Nerve 56 : 1361–1364, 2017" @default.
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- W2607886544 date "2017-05-24" @default.
- W2607886544 modified "2023-10-01" @default.
- W2607886544 title "Quantitative electromyography in ambulatory boys with Duchenne muscular dystrophy" @default.
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- W2607886544 doi "https://doi.org/10.1002/mus.25678" @default.
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