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- W2608110367 endingPage "648" @default.
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- W2608110367 abstract "There are currently no disease-modifying therapies for the treatment of tauopathies, a group of progressive neurodegenerative disorders that are pathologically defined by the presence of tau protein aggregates in the brain. Current challenges for the treatment of tauopathies include the inability to diagnose early and to confidently discriminate between distinct tauopathies in patients, alongside an incomplete understanding of the cellular mechanisms involved in pathogenic tau-induced neuronal death and dysfunction. In this review, we describe current diagnostic and therapeutic strategies, known drivers of pathogenic tau formation, recent contributions to our current mechanistic understanding of how pathogenic tau induces neuronal death, and potential diagnostic and therapeutic approaches." @default.
- W2608110367 created "2017-05-05" @default.
- W2608110367 creator A5044174930 @default.
- W2608110367 creator A5045770248 @default.
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- W2608110367 date "2017-07-01" @default.
- W2608110367 modified "2023-10-14" @default.
- W2608110367 title "A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies" @default.
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