Matches in SemOpenAlex for { <https://semopenalex.org/work/W2608422017> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2608422017 endingPage "131" @default.
- W2608422017 startingPage "124" @default.
- W2608422017 abstract "Five Pinto bean peptides with α-amylase and angiotensin converting enzyme (ACE) inhibitory activities were successfully identified using the integrated bioinformatics approach. By using PEAKS studio, 511 peptide sequences were first shortlisted based on their de novo sequence property and average local confidence (ALC) yield of ≥60%. Subsequently, only five peptides were found to have high potential (score ≥0.80) for contributing bioactivy. The important sites which were potentially bound by the peptides: (a) Trp58, Trp59, Tyr 62, Asp96, Arg195, Asp197, Glu233, His299, Asp300 and His305 for α-amylase; (b) His353, Ala354, His383, Glu384, His387, Glu411, Lys511, His513, Tyr520 and Tyr523 for ACE had corresponded to the catalytic and substrate binding sites of the two enzymes. A validation assay was then conducted and IC50 values were determined. The range of the values for α-amylase inhibitory activity was 10.03–23.33 mM, whereas the values for ACE inhibitory activity were of 1.52–31.88 μM." @default.
- W2608422017 created "2017-05-05" @default.
- W2608422017 creator A5052161638 @default.
- W2608422017 creator A5085314457 @default.
- W2608422017 date "2018-11-01" @default.
- W2608422017 modified "2023-10-16" @default.
- W2608422017 title "Identification of Pinto bean peptides with inhibitory effects on α-amylase and angiotensin converting enzyme (ACE) activities using an integrated bioinformatics-assisted approach" @default.
- W2608422017 cites W114346019 @default.
- W2608422017 cites W1219228310 @default.
- W2608422017 cites W1502426240 @default.
- W2608422017 cites W1925779720 @default.
- W2608422017 cites W1938743025 @default.
- W2608422017 cites W1970431511 @default.
- W2608422017 cites W1977538566 @default.
- W2608422017 cites W1988060353 @default.
- W2608422017 cites W2018491351 @default.
- W2608422017 cites W2036402448 @default.
- W2608422017 cites W2037966597 @default.
- W2608422017 cites W2049616145 @default.
- W2608422017 cites W2080561486 @default.
- W2608422017 cites W2089066209 @default.
- W2608422017 cites W2093974041 @default.
- W2608422017 cites W2094854167 @default.
- W2608422017 cites W2105668062 @default.
- W2608422017 cites W2123651045 @default.
- W2608422017 cites W2128439137 @default.
- W2608422017 cites W2128545763 @default.
- W2608422017 cites W2138216052 @default.
- W2608422017 cites W2192648207 @default.
- W2608422017 cites W2337449073 @default.
- W2608422017 cites W2473717350 @default.
- W2608422017 cites W845847446 @default.
- W2608422017 doi "https://doi.org/10.1016/j.foodchem.2017.04.166" @default.
- W2608422017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29934146" @default.
- W2608422017 hasPublicationYear "2018" @default.
- W2608422017 type Work @default.
- W2608422017 sameAs 2608422017 @default.
- W2608422017 citedByCount "54" @default.
- W2608422017 countsByYear W26084220172018 @default.
- W2608422017 countsByYear W26084220172019 @default.
- W2608422017 countsByYear W26084220172020 @default.
- W2608422017 countsByYear W26084220172021 @default.
- W2608422017 countsByYear W26084220172022 @default.
- W2608422017 countsByYear W26084220172023 @default.
- W2608422017 crossrefType "journal-article" @default.
- W2608422017 hasAuthorship W2608422017A5052161638 @default.
- W2608422017 hasAuthorship W2608422017A5085314457 @default.
- W2608422017 hasConcept C134018914 @default.
- W2608422017 hasConcept C170835558 @default.
- W2608422017 hasConcept C181199279 @default.
- W2608422017 hasConcept C185592680 @default.
- W2608422017 hasConcept C198710026 @default.
- W2608422017 hasConcept C202751555 @default.
- W2608422017 hasConcept C27016395 @default.
- W2608422017 hasConcept C2777752497 @default.
- W2608422017 hasConcept C2779281246 @default.
- W2608422017 hasConcept C55493867 @default.
- W2608422017 hasConcept C84393581 @default.
- W2608422017 hasConcept C86803240 @default.
- W2608422017 hasConceptScore W2608422017C134018914 @default.
- W2608422017 hasConceptScore W2608422017C170835558 @default.
- W2608422017 hasConceptScore W2608422017C181199279 @default.
- W2608422017 hasConceptScore W2608422017C185592680 @default.
- W2608422017 hasConceptScore W2608422017C198710026 @default.
- W2608422017 hasConceptScore W2608422017C202751555 @default.
- W2608422017 hasConceptScore W2608422017C27016395 @default.
- W2608422017 hasConceptScore W2608422017C2777752497 @default.
- W2608422017 hasConceptScore W2608422017C2779281246 @default.
- W2608422017 hasConceptScore W2608422017C55493867 @default.
- W2608422017 hasConceptScore W2608422017C84393581 @default.
- W2608422017 hasConceptScore W2608422017C86803240 @default.
- W2608422017 hasFunder F4320322757 @default.
- W2608422017 hasLocation W26084220171 @default.
- W2608422017 hasLocation W26084220172 @default.
- W2608422017 hasOpenAccess W2608422017 @default.
- W2608422017 hasPrimaryLocation W26084220171 @default.
- W2608422017 hasRelatedWork W155188416 @default.
- W2608422017 hasRelatedWork W1976874022 @default.
- W2608422017 hasRelatedWork W1992009169 @default.
- W2608422017 hasRelatedWork W2005134133 @default.
- W2608422017 hasRelatedWork W2008612314 @default.
- W2608422017 hasRelatedWork W2074022981 @default.
- W2608422017 hasRelatedWork W2103011611 @default.
- W2608422017 hasRelatedWork W2123281989 @default.
- W2608422017 hasRelatedWork W2351543568 @default.
- W2608422017 hasRelatedWork W2382383386 @default.
- W2608422017 hasVolume "267" @default.
- W2608422017 isParatext "false" @default.
- W2608422017 isRetracted "false" @default.
- W2608422017 magId "2608422017" @default.
- W2608422017 workType "article" @default.