Matches in SemOpenAlex for { <https://semopenalex.org/work/W2608493085> ?p ?o ?g. }
- W2608493085 endingPage "29" @default.
- W2608493085 startingPage "23" @default.
- W2608493085 abstract "Retroviral DNA integration takes place in the context of the intasome nucleoprotein complex. X-ray crystal structures of functional spumaviral intasomes were previously revealed to harbor a homotetramer of integrase, and it was generally believed that integrase tetramers catalyzed the integration of other retroviruses. The elucidation of new structures from four different retroviruses over the past year has however revealed this is not the case. The number of integrase molecules required to construct the conserved intasome core structure differs between viral species. While four subunits suffice for spumaviruses, α- and β-retroviruses require eight and the lentiviruses use up to sixteen. Herein we described these alternative architectures, highlighting both evolutionary and structural constraints that result in the different integrase-DNA stoichiometries across Retroviridae." @default.
- W2608493085 created "2017-05-05" @default.
- W2608493085 creator A5043025715 @default.
- W2608493085 creator A5058005825 @default.
- W2608493085 date "2017-12-01" @default.
- W2608493085 modified "2023-10-17" @default.
- W2608493085 title "Retroviral intasomes arising" @default.
- W2608493085 cites W1489055488 @default.
- W2608493085 cites W1501338560 @default.
- W2608493085 cites W1563552185 @default.
- W2608493085 cites W1975535299 @default.
- W2608493085 cites W1997754834 @default.
- W2608493085 cites W1999510588 @default.
- W2608493085 cites W2001281718 @default.
- W2608493085 cites W2006572311 @default.
- W2608493085 cites W2008921565 @default.
- W2608493085 cites W2015180601 @default.
- W2608493085 cites W2025344323 @default.
- W2608493085 cites W2026268551 @default.
- W2608493085 cites W2026862785 @default.
- W2608493085 cites W2027866028 @default.
- W2608493085 cites W2032297596 @default.
- W2608493085 cites W2034741116 @default.
- W2608493085 cites W2038028931 @default.
- W2608493085 cites W2038070445 @default.
- W2608493085 cites W2044418786 @default.
- W2608493085 cites W2044660041 @default.
- W2608493085 cites W2046734228 @default.
- W2608493085 cites W2048072877 @default.
- W2608493085 cites W2056630573 @default.
- W2608493085 cites W2059201099 @default.
- W2608493085 cites W2060369798 @default.
- W2608493085 cites W2072404529 @default.
- W2608493085 cites W2077916498 @default.
- W2608493085 cites W2084629884 @default.
- W2608493085 cites W2085992210 @default.
- W2608493085 cites W2089882643 @default.
- W2608493085 cites W2091648187 @default.
- W2608493085 cites W2113661986 @default.
- W2608493085 cites W2126018286 @default.
- W2608493085 cites W2133670508 @default.
- W2608493085 cites W2139647182 @default.
- W2608493085 cites W2140356633 @default.
- W2608493085 cites W2140854337 @default.
- W2608493085 cites W2143520648 @default.
- W2608493085 cites W2144026217 @default.
- W2608493085 cites W2155439940 @default.
- W2608493085 cites W2275651183 @default.
- W2608493085 cites W2282549557 @default.
- W2608493085 cites W2394600293 @default.
- W2608493085 cites W2519618428 @default.
- W2608493085 cites W2559832357 @default.
- W2608493085 cites W2567957174 @default.
- W2608493085 cites W2568171404 @default.
- W2608493085 doi "https://doi.org/10.1016/j.sbi.2017.04.005" @default.
- W2608493085 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5660667" @default.
- W2608493085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28458055" @default.
- W2608493085 hasPublicationYear "2017" @default.
- W2608493085 type Work @default.
- W2608493085 sameAs 2608493085 @default.
- W2608493085 citedByCount "43" @default.
- W2608493085 countsByYear W26084930852018 @default.
- W2608493085 countsByYear W26084930852019 @default.
- W2608493085 countsByYear W26084930852020 @default.
- W2608493085 countsByYear W26084930852021 @default.
- W2608493085 countsByYear W26084930852022 @default.
- W2608493085 countsByYear W26084930852023 @default.
- W2608493085 crossrefType "journal-article" @default.
- W2608493085 hasAuthorship W2608493085A5043025715 @default.
- W2608493085 hasAuthorship W2608493085A5058005825 @default.
- W2608493085 hasBestOaLocation W26084930852 @default.
- W2608493085 hasConcept C104292427 @default.
- W2608493085 hasConcept C104317684 @default.
- W2608493085 hasConcept C14430832 @default.
- W2608493085 hasConcept C151730666 @default.
- W2608493085 hasConcept C159047783 @default.
- W2608493085 hasConcept C2778481663 @default.
- W2608493085 hasConcept C2779343474 @default.
- W2608493085 hasConcept C2909909245 @default.
- W2608493085 hasConcept C54355233 @default.
- W2608493085 hasConcept C552990157 @default.
- W2608493085 hasConcept C60325843 @default.
- W2608493085 hasConcept C70721500 @default.
- W2608493085 hasConcept C86803240 @default.
- W2608493085 hasConceptScore W2608493085C104292427 @default.
- W2608493085 hasConceptScore W2608493085C104317684 @default.
- W2608493085 hasConceptScore W2608493085C14430832 @default.
- W2608493085 hasConceptScore W2608493085C151730666 @default.
- W2608493085 hasConceptScore W2608493085C159047783 @default.
- W2608493085 hasConceptScore W2608493085C2778481663 @default.
- W2608493085 hasConceptScore W2608493085C2779343474 @default.
- W2608493085 hasConceptScore W2608493085C2909909245 @default.
- W2608493085 hasConceptScore W2608493085C54355233 @default.
- W2608493085 hasConceptScore W2608493085C552990157 @default.
- W2608493085 hasConceptScore W2608493085C60325843 @default.
- W2608493085 hasConceptScore W2608493085C70721500 @default.
- W2608493085 hasConceptScore W2608493085C86803240 @default.
- W2608493085 hasFunder F4320307874 @default.