FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2608839461> ?p ?o ?g. }

• W2608839461 endingPage "854" @default.
• W2608839461 startingPage "854" @default.
• W2608839461 abstract "Following animal model data indicating the possible rejuvenating effects of blood from young donors, there have been at least 2 observational studies conducted with humans that have investigated whether donor age affects patient outcomes. Results, however, have been conflicting.To study the association of donor age and sex with survival of patients receiving transfusions.A retrospective cohort study based on the Scandinavian Donations and Transfusions database, with nationwide data, was conducted for all patients from Sweden and Denmark who received at least 1 red blood cell transfusion of autologous blood or blood from unknown donors between January 1, 2003, and December 31, 2012. Patients were followed up from the first transfusion until death, emigration, or end of follow-up. Data analysis was performed from September 15 to November 15, 2016.The number of transfusions from blood donors of different age and sex. Exposure was treated time dependently throughout follow-up.Hazard ratios (HRs) for death and adjusted cumulative mortality differences, both estimated using Cox proportional hazards regression.Results of a crude analysis including 968 264 transfusion recipients (550 257 women and 418 007 men; median age at first transfusion, 73.0 years [interquartile range, 59.8-82.4 years]) showed a U-shaped association between age of the blood donor and recipient mortality, with a nadir in recipients for the most common donor age group (40-49 years) and significant and increasing HRs among recipients of blood from donors of successively more extreme age groups (<20 years: HR, 1.12; 95% CI, 1.10-1.14; ≥70 years: HR, 1.25; 95% CI, 1.08-1.44). Higher mortality was also noted among recipients of blood from female donors (HR, 1.07; 95% CI, 1.07-1.07). Adjustments for number of transfusions with a linear term attenuated the associations, but the increased mortality for recipients of blood from young, old, and female donors was not eliminated. Closer examination of the association between number of transfusions and mortality revealed a nonlinear pattern. After adjustments to accommodate nonlinearity, donor age and sex were no longer associated with patient mortality.Donor age and sex were not associated with patient survival and need not be considered in blood allocation. Any comparison between common and less common categories of transfusions will inevitably be confounded by the number of transfusions, which drives the probability of receiving the less common blood components. Previous positive findings regarding donor age and sex are most likely explained by residual confounding." @default.
• W2608839461 created "2017-05-05" @default.
• W2608839461 creator A5000020478 @default.
• W2608839461 creator A5016974789 @default.
• W2608839461 creator A5036248073 @default.
• W2608839461 creator A5053718491 @default.
• W2608839461 creator A5053734740 @default.
• W2608839461 creator A5074394409 @default.
• W2608839461 creator A5075852201 @default.
• W2608839461 creator A5090277454 @default.
• W2608839461 date "2017-06-01" @default.
• W2608839461 modified "2023-10-11" @default.
• W2608839461 title "Association of Donor Age and Sex With Survival of Patients Receiving Transfusions" @default.
• W2608839461 cites W1508858234 @default.
• W2608839461 cites W1725613971 @default.
• W2608839461 cites W1779361961 @default.
• W2608839461 cites W1935435746 @default.
• W2608839461 cites W1978670003 @default.
• W2608839461 cites W1978927200 @default.
• W2608839461 cites W1998004606 @default.
• W2608839461 cites W2000445173 @default.
• W2608839461 cites W2003377442 @default.
• W2608839461 cites W2007320066 @default.
• W2608839461 cites W2022487205 @default.
• W2608839461 cites W2023556803 @default.
• W2608839461 cites W2028790836 @default.
• W2608839461 cites W2031212736 @default.
• W2608839461 cites W2035934312 @default.
• W2608839461 cites W2050674783 @default.
• W2608839461 cites W2067028731 @default.
• W2608839461 cites W2107921622 @default.
• W2608839461 cites W2141761576 @default.
• W2608839461 cites W2151125432 @default.
• W2608839461 cites W2156589853 @default.
• W2608839461 cites W2159846037 @default.
• W2608839461 cites W2165037395 @default.
• W2608839461 cites W2186442135 @default.
• W2608839461 cites W2262141841 @default.
• W2608839461 cites W2319373319 @default.
• W2608839461 cites W2470296430 @default.
• W2608839461 cites W2534404687 @default.
• W2608839461 cites W2557069590 @default.
• W2608839461 cites W2563800529 @default.
• W2608839461 doi "https://doi.org/10.1001/jamainternmed.2017.0890" @default.
• W2608839461 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5540056" @default.
• W2608839461 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28437543" @default.
• W2608839461 hasPublicationYear "2017" @default.
• W2608839461 type Work @default.
• W2608839461 sameAs 2608839461 @default.
• W2608839461 citedByCount "62" @default.
• W2608839461 countsByYear W26088394612017 @default.
• W2608839461 countsByYear W26088394612018 @default.
• W2608839461 countsByYear W26088394612019 @default.
• W2608839461 countsByYear W26088394612020 @default.
• W2608839461 countsByYear W26088394612021 @default.
• W2608839461 countsByYear W26088394612022 @default.
• W2608839461 countsByYear W26088394612023 @default.
• W2608839461 crossrefType "journal-article" @default.
• W2608839461 hasAuthorship W2608839461A5000020478 @default.
• W2608839461 hasAuthorship W2608839461A5016974789 @default.
• W2608839461 hasAuthorship W2608839461A5036248073 @default.
• W2608839461 hasAuthorship W2608839461A5053718491 @default.
• W2608839461 hasAuthorship W2608839461A5053734740 @default.
• W2608839461 hasAuthorship W2608839461A5074394409 @default.
• W2608839461 hasAuthorship W2608839461A5075852201 @default.
• W2608839461 hasAuthorship W2608839461A5090277454 @default.
• W2608839461 hasBestOaLocation W26088394611 @default.
• W2608839461 hasConcept C119060515 @default.
• W2608839461 hasConcept C126322002 @default.
• W2608839461 hasConcept C167135981 @default.
• W2608839461 hasConcept C201903717 @default.
• W2608839461 hasConcept C207103383 @default.
• W2608839461 hasConcept C23131810 @default.
• W2608839461 hasConcept C2780014101 @default.
• W2608839461 hasConcept C44249647 @default.
• W2608839461 hasConcept C50382708 @default.
• W2608839461 hasConcept C71924100 @default.
• W2608839461 hasConceptScore W2608839461C119060515 @default.
• W2608839461 hasConceptScore W2608839461C126322002 @default.
• W2608839461 hasConceptScore W2608839461C167135981 @default.
• W2608839461 hasConceptScore W2608839461C201903717 @default.
• W2608839461 hasConceptScore W2608839461C207103383 @default.
• W2608839461 hasConceptScore W2608839461C23131810 @default.
• W2608839461 hasConceptScore W2608839461C2780014101 @default.
• W2608839461 hasConceptScore W2608839461C44249647 @default.
• W2608839461 hasConceptScore W2608839461C50382708 @default.
• W2608839461 hasConceptScore W2608839461C71924100 @default.
• W2608839461 hasIssue "6" @default.
• W2608839461 hasLocation W26088394611 @default.
• W2608839461 hasLocation W26088394612 @default.
• W2608839461 hasLocation W26088394613 @default.
• W2608839461 hasLocation W26088394614 @default.
• W2608839461 hasOpenAccess W2608839461 @default.
• W2608839461 hasPrimaryLocation W26088394611 @default.
• W2608839461 hasRelatedWork W2005101102 @default.
• W2608839461 hasRelatedWork W2114775094 @default.
• W2608839461 hasRelatedWork W2314617070 @default.
• W2608839461 hasRelatedWork W2508300727 @default.

• next