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- W2609005576 abstract "Longitudinal studies of sleep and gastroesophageal reflux disorder (GERD) are scarce. This longitudinal study addresses the question of the place of sleep disorders in the evolution of GERD. Interviews were conducted by phone using the Sleep-EVAL system. Subjects were identified by their physicians or the Sleep-EVAL system as having GERD. The interview included socio-demographic information, sleep-wake schedules and sleeping habits. Sleep disorders were identified according to the DSM-IV-TR and ICSD-2. The sample included 13,937 subjects over 18 years old, representative of the adult population of the 8 most populated states of America. The participation rate was 88%. The longitudinal follow up of the sample took place 3 years after the initial interview. Loss at follow up was inferior to 10.5%. The prevalence of GERD significantly increased with age between Wave 1 and Wave 2: 6% of the total sample reported GERD only at wave 1, 8.5% reported GERD only at Wave 2, and 3.9% reported GERD both at Wave 1 and Wave 2. Insomnia disorder is present at Wave 1 and Wave 2 in 24.5% of the population. At Wave 1 and Wave 2, GERD subjects had high prevalence of sleep dissatisfaction (24.2%), difficulty initiating sleep (15.2%) and non-restorative sleep (15.6%). Nocturnal awakening (33.9%) is the most prevalent symptom associated with GERD. Obstructive Sleep Apnea, Restless Leg Syndrome and Obesity were frequently and significantly associated with GERD. The longitudinal investigation of the interaction of GERD and Sleep shows that Sleep is a good predictor of of GERD chronicity. In the second wave of this study, the sleep disturbances induced initially by GERD increase the severity of GERD and contribute to its chronicity. Unrestricted educational grants from the John Arrillaga Foundation and Takeda Pharmaceuticals." @default.
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- W2609005576 date "2017-04-28" @default.
- W2609005576 modified "2023-10-14" @default.
- W2609005576 title "1029 LONGITUDINAL STUDY OF THE INTERACTION BETWEEN SLEEP AND GASTROESOPHAGEAL REFLUX DISORDER IN THE US GENERAL POPULATION" @default.
- W2609005576 doi "https://doi.org/10.1093/sleepj/zsx050.1028" @default.
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