FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2609235087> ?p ?o ?g. }

• W2609235087 endingPage "1415" @default.
• W2609235087 startingPage "1403" @default.
• W2609235087 abstract "New strategies to control cholera are urgently needed. This study develops an in vitro proof-of-concept sense-and-kill system in a wild-type Escherichia coli strain to target the causative pathogen Vibrio cholerae using a synthetic biology approach. Our engineered E. coli specifically detects V. cholerae via its quorum-sensing molecule CAI-1 and responds by expressing the lysis protein YebF-Art-085, thereby self-lysing to release the killing protein Art-085 to kill V. cholerae. For this report, we individually characterized YebF-Art-085 and Art-085 expression and their activities when coupled to our previously developed V. cholerae biosensing circuit. We show that, in the presence of V. cholerae supernatant, the final integrated sense-and-kill system in our engineered E. coli can effectively inhibit the growth of V. cholerae cells. This work represents the first step toward a novel probiotic treatment modality that could potentially prevent and treat cholera in the future." @default.
• W2609235087 created "2017-05-05" @default.
• W2609235087 creator A5017996912 @default.
• W2609235087 creator A5038903299 @default.
• W2609235087 creator A5050680934 @default.
• W2609235087 creator A5071085698 @default.
• W2609235087 creator A5079052023 @default.
• W2609235087 date "2017-05-05" @default.
• W2609235087 modified "2023-09-29" @default.
• W2609235087 title "Repurposing a Two-Component System-Based Biosensor for the Killing of <i>Vibrio cholerae</i>" @default.
• W2609235087 cites W1826531932 @default.
• W2609235087 cites W1927570869 @default.
• W2609235087 cites W1968342623 @default.
• W2609235087 cites W1971439989 @default.
• W2609235087 cites W1972447176 @default.
• W2609235087 cites W1982072530 @default.
• W2609235087 cites W1986134153 @default.
• W2609235087 cites W2008853726 @default.
• W2609235087 cites W2010980975 @default.
• W2609235087 cites W2016402044 @default.
• W2609235087 cites W2036176224 @default.
• W2609235087 cites W2042116577 @default.
• W2609235087 cites W2048955235 @default.
• W2609235087 cites W2084623901 @default.
• W2609235087 cites W2086474106 @default.
• W2609235087 cites W2090627629 @default.
• W2609235087 cites W2099062342 @default.
• W2609235087 cites W2107523606 @default.
• W2609235087 cites W2107943090 @default.
• W2609235087 cites W2112988492 @default.
• W2609235087 cites W2118464978 @default.
• W2609235087 cites W2126588228 @default.
• W2609235087 cites W2131096375 @default.
• W2609235087 cites W2142809851 @default.
• W2609235087 cites W2143337671 @default.
• W2609235087 cites W2151004546 @default.
• W2609235087 cites W2152343141 @default.
• W2609235087 cites W2153843103 @default.
• W2609235087 cites W2160051211 @default.
• W2609235087 cites W2160237938 @default.
• W2609235087 cites W2165784284 @default.
• W2609235087 cites W2183977847 @default.
• W2609235087 cites W2320694902 @default.
• W2609235087 cites W2342118510 @default.
• W2609235087 cites W2344843461 @default.
• W2609235087 cites W2346821352 @default.
• W2609235087 cites W2517580947 @default.
• W2609235087 cites W4211176329 @default.
• W2609235087 cites W4239215074 @default.
• W2609235087 doi "https://doi.org/10.1021/acssynbio.7b00058" @default.
• W2609235087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28441472" @default.
• W2609235087 hasPublicationYear "2017" @default.
• W2609235087 type Work @default.
• W2609235087 sameAs 2609235087 @default.
• W2609235087 citedByCount "54" @default.
• W2609235087 countsByYear W26092350872018 @default.
• W2609235087 countsByYear W26092350872019 @default.
• W2609235087 countsByYear W26092350872020 @default.
• W2609235087 countsByYear W26092350872021 @default.
• W2609235087 countsByYear W26092350872022 @default.
• W2609235087 countsByYear W26092350872023 @default.
• W2609235087 crossrefType "journal-article" @default.
• W2609235087 hasAuthorship W2609235087A5017996912 @default.
• W2609235087 hasAuthorship W2609235087A5038903299 @default.
• W2609235087 hasAuthorship W2609235087A5050680934 @default.
• W2609235087 hasAuthorship W2609235087A5071085698 @default.
• W2609235087 hasAuthorship W2609235087A5079052023 @default.
• W2609235087 hasConcept C104317684 @default.
• W2609235087 hasConcept C118687296 @default.
• W2609235087 hasConcept C18903297 @default.
• W2609235087 hasConcept C2777006276 @default.
• W2609235087 hasConcept C2778643871 @default.
• W2609235087 hasConcept C2780722889 @default.
• W2609235087 hasConcept C519536355 @default.
• W2609235087 hasConcept C523546767 @default.
• W2609235087 hasConcept C54355233 @default.
• W2609235087 hasConcept C547475151 @default.
• W2609235087 hasConcept C55493867 @default.
• W2609235087 hasConcept C57409179 @default.
• W2609235087 hasConcept C58123911 @default.
• W2609235087 hasConcept C86803240 @default.
• W2609235087 hasConcept C89423630 @default.
• W2609235087 hasConceptScore W2609235087C104317684 @default.
• W2609235087 hasConceptScore W2609235087C118687296 @default.
• W2609235087 hasConceptScore W2609235087C18903297 @default.
• W2609235087 hasConceptScore W2609235087C2777006276 @default.
• W2609235087 hasConceptScore W2609235087C2778643871 @default.
• W2609235087 hasConceptScore W2609235087C2780722889 @default.
• W2609235087 hasConceptScore W2609235087C519536355 @default.
• W2609235087 hasConceptScore W2609235087C523546767 @default.
• W2609235087 hasConceptScore W2609235087C54355233 @default.
• W2609235087 hasConceptScore W2609235087C547475151 @default.
• W2609235087 hasConceptScore W2609235087C55493867 @default.
• W2609235087 hasConceptScore W2609235087C57409179 @default.
• W2609235087 hasConceptScore W2609235087C58123911 @default.
• W2609235087 hasConceptScore W2609235087C86803240 @default.
• W2609235087 hasConceptScore W2609235087C89423630 @default.
• W2609235087 hasFunder F4320320751 @default.

• next